Progress in neuro-psychopharmacology & biological psychiatry
Jul 25, 2021
Zebrafish (Danio rerio) are rapidly emerging in biomedicine as promising tools for disease modelling and drug discovery. The use of zebrafish for neuroscience research is also growing rapidly, necessitating novel reliable and unbiased methods of neur...
Progress in neuro-psychopharmacology & biological psychiatry
Oct 9, 2020
BACKGROUND: Mood disorders (major depressive disorder, MDD, and bipolar disorder, BD) are considered leading causes of life-long disability worldwide, where high rates of no response to treatment or relapse and delays in receiving a proper diagnosis ...
Progress in neuro-psychopharmacology & biological psychiatry
Aug 18, 2020
BACKGROUND: Altered structural and functional brain networks have been extensively studied in major depressive disorder (MDD) patients. However, whether the differential connectivity patterns in the rich-club organization, assessed from structural br...
Progress in neuro-psychopharmacology & biological psychiatry
Aug 14, 2020
Electroencephalography (EEG) based biomarkers have been shown to correlate with the presence of psychotic disorders. Increased delta and decreased alpha power in psychosis indicate an abnormal arousal state. We investigated brain activity across the ...
Progress in neuro-psychopharmacology & biological psychiatry
Jul 25, 2019
There is a growing need to address the variability in detecting cognitive deficits with standard tests in cocaine dependence (CD). The aim of the current study was to identify cognitive deficits by means of Machine Learning (ML) algorithms: Generaliz...
Progress in neuro-psychopharmacology & biological psychiatry
Oct 2, 2018
Despite its initial promise, neuroimaging has not been widely translated into clinical psychiatry to assist in the prediction of diagnoses, prognoses, and optimal therapeutic strategies. Machine learning approaches may enhance the translational poten...
Progress in neuro-psychopharmacology & biological psychiatry
Jun 26, 2018
BACKGROUND: Recent studies demonstrate that functional disruption in resting-state networks contributes to cognitive and affective symptoms of bipolar disorder (BD), however, the functional connectivity (FC) pattern underlying BD II depression within...
Progress in neuro-psychopharmacology & biological psychiatry
Jun 23, 2017
Mood disorders are a highly prevalent group of mental disorders causing substantial socioeconomic burden. There are various methodological approaches for identifying the underlying mechanisms of the etiology, symptomatology, and therapeutics of mood ...
Progress in neuro-psychopharmacology & biological psychiatry
Feb 20, 2017
OBJECTIVE: Major depressive disorder (MDD) is a systemic and multifactorial disorder that involves abnormalities in multiple biochemical pathways and the autonomic nervous system. This study applied a machine-learning method to classify MDD and contr...