AIMC Topic: Adenocarcinoma

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Establishment of two pathomic-based machine learning models to predict CLCA1 expression in colon adenocarcinoma.

PloS one
Chloride channel accessory 1 (CLCA1) is considered a potential prognostic biomarker for colon adenocarcinoma (COAD). The objective of this research was to develop two pathomics models to predict CLCA1 expression from hematoxylin-eosin (H&E) stained p...

Development and validation of CT-based fusion model for preoperative prediction of invasion and lymph node metastasis in adenocarcinoma of esophagogastric junction.

BMC medical imaging
PURPOSE: In the context of precision medicine, radiomics has become a key technology in solving medical problems. For adenocarcinoma of esophagogastric junction (AEG), developing a preoperative CT-based prediction model for AEG invasion and lymph nod...

A hybrid multi-instance learning-based identification of gastric adenocarcinoma differentiation on whole-slide images.

Biomedical engineering online
OBJECTIVE: To investigate the potential of a hybrid multi-instance learning model (TGMIL) combining Transformer and graph attention networks for classifying gastric adenocarcinoma differentiation on whole-slide images (WSIs) without manual annotation...

Biomarker risk stratification with capsule sponge in the surveillance of Barrett's oesophagus: prospective evaluation of UK real-world implementation.

Lancet (London, England)
BACKGROUND: Endoscopic surveillance is the clinical standard for Barrett's oesophagus, but its effectiveness is inconsistent. We have developed a test comprising a pan-oesophageal cell collection device coupled with biomarkers to stratify patients in...

[Incidental pulmonary nodules on CT imaging: what to do?].

Nederlands tijdschrift voor geneeskunde
Incidental pulmonary nodules are very frequently found on CT imaging and may represent (early stage) lung cancers without any signs or symptoms. These incidental findings can be solid lesions or ground glass lesions that may be solitary or multiple. ...

Immunohistochemical biomarker scoring in gastroesophageal cancers: Can computers help us?

Pathology, research and practice
The increasing complexity of cancer diagnostics and treatment selection has placed a growing burden on pathologists, particularly in the evaluation of immunohistochemical (IHC) biomarkers. In gastroesophageal cancers (GEC), both adenocarcinoma and sq...

Prediction of Tumor Budding Grading in Rectal Cancer Using a Multiparametric MRI Radiomics Combined with a 3D Vision Transformer Deep Learning Approach.

Academic radiology
RATIONALE AND OBJECTIVES: The objective is to assess the effectiveness of a multiparametric MRI radiomics strategy combined with a 3D Vision Transformer (ViT) deep learning (DL) model in predicting tumor budding (TB) grading in individuals diagnosed ...

Development and application of deep learning-based diagnostics for pathologic diagnosis of gastric endoscopic submucosal dissection specimens.

Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association
BACKGROUND: Accurate diagnosis of ESD specimens is crucial for managing early gastric cancer. Identifying tumor areas in serially sectioned ESD specimens requires experience and is time-consuming. This study aimed to develop and evaluate a deep learn...