AIMC Topic: Aged, 80 and over

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The effect of psychotherapy on the multivariate association between insomnia and depressive symptoms in late-life depression.

European psychiatry : the journal of the Association of European Psychiatrists
BACKGROUND: Late-life depression (LLD) is prevalent in older adults and linked to increased disability, mortality, and suicide risk. Insomnia symptoms are considered common remaining symptoms of LLD following treatment. However, the multivariate rela...

Explainable mortality prediction models incorporating social health determinants and physical frailty for heart failure patients.

PloS one
There is limited evidence on how social determinants of health (SDOH) and physical frailty (PF) influence mortality prediction in heart failure (HF), particularly for in-hospital, 90-day, and 1-year outcomes. This study aims to develop explainable ma...

Pulmonary Embolism Survival Prediction Using Multimodal Learning Based on Computed Tomography Angiography and Clinical Data.

Journal of thoracic imaging
PURPOSE: Pulmonary embolism (PE) is a significant cause of mortality in the United States. The objective of this study is to implement deep learning (DL) models using computed tomography pulmonary angiography (CTPA), clinical data, and PE Severity In...

Factors associated with admission to elderly medical-welfare facilities in South Korea: a cross-sectional machine-learning study.

BMJ open
OBJECTIVES: To identify the key factors associated with admission to elderly medical-welfare facilities in South Korea and to evaluate their relative importance using machine learning techniques, providing an evidence base for policy in a rapidly age...

External validation of deep learning-derived 18F-FDG PET/CT delta biomarkers for loco-regional control in head and neck cancer.

Acta oncologica (Stockholm, Sweden)
BACKGROUND AND PURPOSE: Delta biomarkers that reflect changes in tumour burden over time can support personalised follow-up in head and neck cancer. However, their clinical use can be limited by the need for manual image segmentation. This study exte...

Deep Learning Radiomics Model Based on Computed Tomography Image for Predicting the Classification of Osteoporotic Vertebral Fractures: Algorithm Development and Validation.

JMIR medical informatics
BACKGROUND: Osteoporotic vertebral fractures (OVFs) are common in older adults and often lead to disability if not properly diagnosed and classified. With the increased use of computed tomography (CT) imaging and the development of radiomics and deep...

Evaluating the Feasibility of a Dyadic, Touch-Based Multimedia Tablet Intervention and Its Effects on the Caregiver-Patient Relationship Among Individuals With Mild Cognitive Impairment: Qualitative Triangulation Study.

JMIR aging
BACKGROUND: Approximately 20% of the global population is affected by mild cognitive impairment (MCI), with around 15% progressing to dementia within 2 years. Touch-based multimedia applications can support cognitive, social, and physical functioning...

Exploring the potential relationship between kidney disease index and cognitive dysfunction: a machine learning approach with NHANES data.

BMC geriatrics
OBJECTIVE: This study investigates the relationship between the Kidney Disease Index (KDI) and cognitive function, evaluating its potential as a predictive marker for cognitive impairment in older adults. We also compare the performance of KDI with t...

Development of a deep learning method to identify acute ischaemic stroke lesions on brain CT.

Stroke and vascular neurology
BACKGROUND: CT is commonly used to image patients with ischaemic stroke but radiologist interpretation may be delayed. Machine learning techniques can provide rapid automated CT assessment but are usually developed from annotated images which necessa...

Causal effect of conventional anti-dementia drugs on economic burden: an orthogonal double/debiased machine learning approach.

BMC geriatrics
BACKGROUND: The Inflation Reduction Act (IRA) did not introduce a cap on out-of-pocket (OOP) for newly approved Alzheimer's Disease (AD) drugs, such as lecanemab which is covered under Medicare Part B. Therefore, expanding the use of conventional ant...