AIMC Topic: Aged

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Spatial characterization of tertiary lymphoid structures as predictive biomarkers for immune checkpoint blockade in head and neck squamous cell carcinoma.

Oncoimmunology
Immune checkpoint blockade (ICB) is the standard of care for recurrent/metastatic head and neck squamous cell carcinoma (HNSCC), yet efficacy remains low. The combined positive score (CPS) for PD-L1 is the only biomarker approved to predict response ...

Moving Beyond CT Body Composition Analysis: Using Style Transfer for Bringing CT-Based Fully-Automated Body Composition Analysis to T2-Weighted MRI Sequences.

Investigative radiology
OBJECTIVES: Deep learning for body composition analysis (BCA) is gaining traction in clinical research, offering rapid and automated ways to measure body features like muscle or fat volume. However, most current methods prioritize computed tomography...

Deep Learning-Based Signal Amplification of T1-Weighted Single-Dose Images Improves Metastasis Detection in Brain MRI.

Investigative radiology
OBJECTIVES: Double-dose contrast-enhanced brain imaging improves tumor delineation and detection of occult metastases but is limited by concerns about gadolinium-based contrast agents' effects on patients and the environment. The purpose of this stud...

Impact of Sepsis Onset Timing on All-Cause Mortality in Acute Pancreatitis: A Multicenter Retrospective Cohort Study.

Journal of intensive care medicine
BackgroundSepsis complicates acute pancreatitis (AP), increasing mortality risk. Few studies have examined how sepsis and its onset timing affect mortality in AP. This study evaluates the association between sepsis occurrence and all-cause mortality ...

IRMA: Machine learning-based harmonization of F-FDG PET brain scans in multi-center studies.

European journal of nuclear medicine and molecular imaging
PURPOSE: Center-specific effects in PET brain scans arise due to differences in technical and procedural aspects. This restricts the merging of data between centers and introduces source-specific bias.

Automated quantification of brain PET in PET/CT using deep learning-based CT-to-MR translation: a feasibility study.

European journal of nuclear medicine and molecular imaging
PURPOSE: Quantitative analysis of PET images in brain PET/CT relies on MRI-derived regions of interest (ROIs). However, the pairs of PET/CT and MR images are not always available, and their alignment is challenging if their acquisition times differ c...

Clinical efficacy of NIBS in enhancing neuroplasticity for stroke recovery.

Journal of neuroscience methods
BACKGROUND: For stroke patients, a therapeutic approach named Non-invasive brain stimulation (NIBS) was applied and it has gained attention. This NIBS approach enhances the neuroplasticity and facilitates in functional Stroke Rehabilitation (SR) thro...

Interpretation of basal nuclei in brain dopamine transporter scans using a deep convolutional neural network.

Nuclear medicine communications
OBJECTIVE: Functional imaging using the dopamine transporter (DAT) as a biomarker has proven effective in assessing dopaminergic neuron degeneration in the striatum. In assessing the neuron degeneration, visual and semiquantitative methods are used t...

Intelligent Verification Tool for Surgical Information of Ophthalmic Patients: A Study Based on Artificial Intelligence Technology.

Journal of patient safety
OBJECTIVE: With the development of day surgery, the characteristics of "short, frequent and fast" ophthalmic surgery are becoming more prominent. However, nurses are not efficient in verifying patients' surgical information, and problems such as pati...

Predicting malignant risk of ground-glass nodules using convolutional neural networks based on dual-time-point F-FDG PET/CT.

Cancer imaging : the official publication of the International Cancer Imaging Society
BACKGROUND: Accurately predicting the malignant risk of ground-glass nodules (GGOs) is crucial for precise treatment planning. This study aims to utilize convolutional neural networks based on dual-time-point F-FDG PET/CT to predict the malignant ris...