AIMC Topic: Aged

Clear Filters Showing 561 to 570 of 13244 articles

Early detection of Alzheimer's disease using small RNAs. Results from the EPAD cohort.

The journal of prevention of Alzheimer's disease
BACKGROUND: Alzheimer's disease (AD) is the most common form of dementia, and early diagnosis is crucial to enable effective interventions. Currently, Alzheimer's disease is diagnosed through cognitive assessments, brain imaging and fluid biomarkers ...

Explainable classification of Parkinson's disease with different motor subtypes by analyzing the synthetic MRI quantitative parameters of subcortical nuclei.

European journal of radiology
OBJECTIVES: To explore differences in quantitative parameters of subcortical nuclei using synthetic MRI across different motor subtypes of Parkinson's Disease (PD), and to develop an interpretable model for distinguishing PD subtypes.

Regional cortical thinning and area reduction are associated with cognitive impairment in hemodialysis patients.

Brain research bulletin
Magnetic resonance imaging (MRI) has shown that patients with end-stage renal disease have decreased gray matter volume and density. However, the cortical area and thickness in patients on hemodialysis are uncertain, and the relationship between pati...

A comprehensive hybrid model: Combining bioinspired optimization and deep learning for Alzheimer's disease identification.

Computers in biology and medicine
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by a gradual decline in cognitive ability and memory function. It is a progressive disease characterized by worsening dementia symptoms over time, starting with mild m...

Artificial Intelligence-Based Detection of Central Retinal Artery Occlusion Within 4.5 Hours on Standard Fundus Photographs.

Journal of the American Heart Association
BACKGROUND: Prompt diagnosis of acute central retinal artery occlusion (CRAO) is crucial for therapeutic management and stroke prevention. However, most stroke centers lack onsite ophthalmic expertise before considering fibrinolytic treatment. This s...

Radiomic 'Stress Test': exploration of a deep learning radiomic model in a high-risk prospective lung nodule cohort.

BMJ open respiratory research
BACKGROUND: Indeterminate pulmonary nodules (IPNs) are commonly biopsied to ascertain a diagnosis of lung cancer, but many are ultimately benign. The Lung Cancer Prediction (LCP) score is a commercially available deep learning radiomic model with str...

A Responsible Framework for Assessing, Selecting, and Explaining Machine Learning Models in Cardiovascular Disease Outcomes Among People With Type 2 Diabetes: Methodology and Validation Study.

JMIR medical informatics
BACKGROUND: Building machine learning models that are interpretable, explainable, and fair is critical for their trustworthiness in clinical practice. Interpretability, which refers to how easily a human can comprehend the mechanism by which a model ...

Using Artificial Intelligence to assess the impact of social, physical, and financial health and personality on subjective well-being in a representative, multinational sample of older European and Israeli adults.

Journal of global health
BACKGROUND: Subjective well-being (SWB) is an important outcome influenced by other aspects of health and personality. However, we know little about the independent effects of multiple health and personality dimensions on SWB in large, representative...