OBJECTIVE: This study aimed to validate and optimize a machine learning algorithm for accurately predicting low-density lipoprotein cholesterol (LDL-C) levels, addressing limitations of traditional formulas, particularly in hypertriglyceridemia.
BACKGROUND: Head and neck cancer (HNC) becomes a vital global health burden. Accurate assessment of the disease burden plays an essential role in setting health priorities and guiding decision-making.
This study aimed to develop models for predicting the 30-day mortality of sepsis-associated delirium (SAD) by multiple machine learning (ML) algorithms. On the whole, a cohort of 3,197 SAD patients were collected from the Medical Information Mart for...
International journal of medical informatics
Apr 8, 2025
BACKGROUND: In light of global population aging and the increasing prevalence of Rheumatoid Arthritis (RA) with age, strategies are needed to address this public health challenge. Machine learning (ML) may play a vital role in early identification of...
Clinical pharmacology and therapeutics
Apr 8, 2025
Measuring medication discontinuation in claims data primarily relies on the gaps between prescription fills, but such definitions are rarely validated. This study aimed to establish a natural language processing (NLP)-based validation framework to ev...
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Apr 8, 2025
BACKGROUND AND PURPOSE: To establish predictive models for radiation-induced hypoglossal neuropathy (RIHN) in patients with nasopharyngeal carcinoma (NPC) after intensity-modulated radiotherapy (IMRT).
BACKGROUND: Predicting the prognosis of patients with acute myocardial infarction (AMI) combined with diabetes mellitus (DM) is crucial due to high in-hospital mortality rates. This study aims to develop and validate a mortality risk prediction model...
In digital radiography, image quality is synergistically affected by anatomy-specific examinations, exposure factors, body parameters, detector types, and vendors/systems. However, estimating appropriate exposure factors before radiography with optim...
N-Terminal Pro-Brain Natriuretic Peptide (NT-proBNP) is important for diagnosing and predicting heart failure or many other diseases. However, few studies have comprehensively assessed the factors correlated with NT-proBNP levels in people with cardi...
BACKGROUND: T-cell receptor (TCR) repertoires provide insights into tumor immunology, yet their variations across digestive system cancers are not well understood. Characterizing TCR differences between colorectal cancer (CRC) and gastric cancer (GC)...
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