AIMC Topic: Aged

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Machine learning-based prediction of LDL cholesterol: performance evaluation and validation.

PeerJ
OBJECTIVE: This study aimed to validate and optimize a machine learning algorithm for accurately predicting low-density lipoprotein cholesterol (LDL-C) levels, addressing limitations of traditional formulas, particularly in hypertriglyceridemia.

Global burden and future trends of head and neck cancer: a deep learning-based analysis (1980-2030).

PloS one
BACKGROUND: Head and neck cancer (HNC) becomes a vital global health burden. Accurate assessment of the disease burden plays an essential role in setting health priorities and guiding decision-making.

Machine learning approach for the prediction of 30-day mortality in patients with sepsis-associated delirium.

PloS one
This study aimed to develop models for predicting the 30-day mortality of sepsis-associated delirium (SAD) by multiple machine learning (ML) algorithms. On the whole, a cohort of 3,197 SAD patients were collected from the Medical Information Mart for...

Predicting rheumatoid arthritis in the middle-aged and older population using patient-reported outcomes: insights from the SHARE cohort.

International journal of medical informatics
BACKGROUND: In light of global population aging and the increasing prevalence of Rheumatoid Arthritis (RA) with age, strategies are needed to address this public health challenge. Machine learning (ML) may play a vital role in early identification of...

Establishing a Validation Framework of Treatment Discontinuation in Claims Data Using Natural Language Processing and Electronic Health Records.

Clinical pharmacology and therapeutics
Measuring medication discontinuation in claims data primarily relies on the gaps between prescription fills, but such definitions are rarely validated. This study aimed to establish a natural language processing (NLP)-based validation framework to ev...

Development and validation of Prediction models for radiation-induced hypoglossal neuropathy in patients with nasopharyngeal carcinoma.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
BACKGROUND AND PURPOSE: To establish predictive models for radiation-induced hypoglossal neuropathy (RIHN) in patients with nasopharyngeal carcinoma (NPC) after intensity-modulated radiotherapy (IMRT).

Application of an interpretable machine learning method to predict the risk of death during hospitalization in patients with acute myocardial infarction combined with diabetes mellitus.

Acta cardiologica
BACKGROUND: Predicting the prognosis of patients with acute myocardial infarction (AMI) combined with diabetes mellitus (DM) is crucial due to high in-hospital mortality rates. This study aims to develop and validate a mortality risk prediction model...

An artificial intelligence model for predicting an appropriate mAs with target exposure indicator for chest digital radiography.

Scientific reports
In digital radiography, image quality is synergistically affected by anatomy-specific examinations, exposure factors, body parameters, detector types, and vendors/systems. However, estimating appropriate exposure factors before radiography with optim...

Machine learning integration of multimodal data identifies key features of circulating NT-proBNP in people without cardiovascular diseases.

Scientific reports
N-Terminal Pro-Brain Natriuretic Peptide (NT-proBNP) is important for diagnosing and predicting heart failure or many other diseases. However, few studies have comprehensively assessed the factors correlated with NT-proBNP levels in people with cardi...

T-cell receptor dynamics in digestive system cancers: a multi-layer machine learning approach for tumor diagnosis and staging.

Frontiers in immunology
BACKGROUND: T-cell receptor (TCR) repertoires provide insights into tumor immunology, yet their variations across digestive system cancers are not well understood. Characterizing TCR differences between colorectal cancer (CRC) and gastric cancer (GC)...