AIMC Topic: Aged

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Association of TLR 9 gene polymorphisms with remission in patients with rheumatoid arthritis receiving TNF-α inhibitors and development of machine learning models.

Scientific reports
Toll-like receptor (TLR)-4 and TLR9 are known to play important roles in the immune system, and several studies have shown their association with the development of rheumatoid arthritis (RA) and regulation of tumor necrosis factor alpha (TNF-α). Howe...

Perception of yips among professional Japanese golfers: perspectives from a network modelled approach.

Scientific reports
'Yips' in golf is a complex spectrum of anxiety and movement-disorder that affects competitive sporting performance. With unclear etiology and high prevalence documented in western literature, the perception and management of this psycho-neuromuscula...

Predicting bloodstream infection outcome using machine learning.

Scientific reports
Bloodstream infections (BSI) are a main cause of infectious disease morbidity and mortality worldwide. Early prediction of BSI patients at high risk of poor outcomes is important for earlier decision making and effective patient stratification. We de...

Improved prediction of smoking status via isoform-aware RNA-seq deep learning models.

PLoS computational biology
Most predictive models based on gene expression data do not leverage information related to gene splicing, despite the fact that splicing is a fundamental feature of eukaryotic gene expression. Cigarette smoking is an important environmental risk fac...

Application of Medical Imaging Based on Deep Learning in the Treatment of Lumbar Degenerative Diseases and Osteoporosis with Bone Cement Screws.

Computational and mathematical methods in medicine
OBJECTIVE: To explore the application value of magnetic resonance spectroscopy (MRS) and GSI-energy spectrum electronic computed tomography (CT) medical imaging based on the deep convolutional neural network (CNN) in the treatment of lumbar degenerat...

Clinical and Radiologic Outcomes of Robot-Assisted Kyphoplasty versus Fluoroscopy-Assisted Kyphoplasty in the Treatment of Osteoporotic Vertebral Compression Fractures: A Retrospective Comparative Study.

World neurosurgery
BACKGROUND: Making surgery as less aggressive as possible is best for elderly patients with osteoporotic vertebral compression fractures (OVCFs). Recently, we attempted a more precise, minimally invasive, and robot-assisted kyphoplasty in our clinica...

Predicting microvascular invasion in hepatocellular carcinoma: a deep learning model validated across hospitals.

Cancer imaging : the official publication of the International Cancer Imaging Society
BACKGROUND: The accuracy of estimating microvascular invasion (MVI) preoperatively in hepatocellular carcinoma (HCC) by clinical observers is low. Most recent studies constructed MVI predictive models utilizing radiological and/or radiomics features ...

Improved Prediction of Older Adult Discharge After Trauma Using a Novel Machine Learning Paradigm.

The Journal of surgical research
BACKGROUND: The ability to reliably predict outcomes after trauma in older adults (age ≥ 65 y) is critical for clinical decision making. Using novel machine-learning techniques, we sought to design a nonlinear, competing risks paradigm for prediction...

Deep learning based multiplexed sensitivity-encoding (DL-MUSE) for high-resolution multi-shot DWI.

NeuroImage
PURPOSE: A phase correction method for high-resolution multi-shot (MSH) diffusion weighted imaging (DWI) is proposed. The efficacy and generalization capability of the method were validated on both healthy volunteers and patients.

Feasibility and tolerance of a robotic postural training to improve standing in a person with ambulatory spinal cord injury.

Spinal cord series and cases
An ambulatory elder with SCI, AIS C, balance deficits, and right ankle-foot-orthosis participated. RobUST-intervention comprised six 90 min-sessions of postural tasks with pelvic assistance and trunk perturbations. We collected three baselines and tw...