AIMC Topic: Animals

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Using human in vitro transcriptome analysis to build trustworthy machine learning models for prediction of animal drug toxicity.

Scientific reports
During the development of new drugs or compounds there is a requirement for preclinical trials, commonly involving animal tests, to ascertain the safety of the compound prior to human trials. Machine learning techniques could provide an in-silico alt...

A Novel Robotic Endoscopic Device Used for Operative Hysteroscopy.

Journal of minimally invasive gynecology
To trial the use of a novel endoscopic robot that functions using concentric tube robots, enabling 2-handed surgery in small spaces, in a bioengineering laboratory. This was a feasibility study of the endoscopic robot for hysteroscopic applications, ...

Comparing the Bone Healing After Cold Ablation Robot-Guided Er:YAG Laser Osteotomy and Piezoelectric Osteotomy-A Pilot Study in a Minipig Mandible.

Lasers in surgery and medicine
BACKGROUND AND OBJECTIVE: To take major advantage of erbium-doped yttrium aluminium garnet (Er:YAG) lasers in osteotomy-like freedom of cutting geometries and high accuracy-the integration and miniaturization of the robot, laser, and navigation techn...

Untethered-Bioinspired Quadrupedal Robot Based on Double-Chamber Pre-charged Pneumatic Soft Actuators with Highly Flexible Trunk.

Soft robotics
Given that mobile soft robots are adaptable to the environment, they are always tethered with slow locomotion speed. Compared with other types of mobile robots, mobile soft robots may be more suitable for rescuing tasks, accompanying elderly people, ...

Manufacturing, Control, and Performance Evaluation of a Gecko-Inspired Soft Robot.

Journal of visualized experiments : JoVE
This protocol presents a method for manufacturing, control, and evaluation of the performance of a soft robot that can climb inclined flat surfaces with slopes of up to 84°. The manufacturing method is valid for the fast pneunet bending actuators in ...

Distinct signals in medial and lateral VTA dopamine neurons modulate fear extinction at different times.

eLife
Dopamine (DA) neurons are to encode reward prediction error (RPE), in addition to other signals, such as salience. While RPE is known to support learning, the role of salience in learning remains less clear. To address this, we recorded and manipulat...

Artificial intelligence for breast cancer detection in mammography and digital breast tomosynthesis: State of the art.

Seminars in cancer biology
Screening for breast cancer with mammography has been introduced in various countries over the last 30 years, initially using analog screen-film-based systems and, over the last 20 years, transitioning to the use of fully digital systems. With the in...

A Coupled FEM-SPH Modeling Technique to Investigate the Contractility of Biohybrid Thin Films.

Advanced biosystems
Biohybrid actuators have the potential to overcome the limitations of traditional actuators employed in robotics, thanks to the unique features of living contractile muscle cells, which can be used to power artificial elements. This paper describes a...

Fish-like aquatic propulsion studied using a pneumatically-actuated soft-robotic model.

Bioinspiration & biomimetics
Fish locomotion is characterized by waves of muscle electrical activity that proceed from head to tail, and result in an undulatory pattern of body bending that generates thrust during locomotion. Isolating the effects of parameters like body stiffne...

Development of an annelid-like peristaltic crawling soft robot using dielectric elastomer actuators.

Bioinspiration & biomimetics
The annelid, which consists of several identical segments, exploits its soft structures to move effectively in complex natural environments. Elongation and shortening of different segments produce a reverse peristaltic wave while retractable setae ge...