AIMC Topic: Antioxidants

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Benchtop Vis-NIR spectroscopy meets machine learning for multi-task analysis in Hongmeiren citrus: Geographical origin identification and antioxidant component quantification.

Food chemistry
Due to geographical indication advantage of Hongmeiren (HMR) citrus, economically motivated origin fraud has emerged, alongside significant differences in antioxidant components. This study employed benchtop visible and near-infrared (Vis-NIR) spectr...

Antioxidant bioactivity of sunflower protein hydrolysates in Caco-2 cells and in silico structural properties.

Food chemistry
Sunflower protein hydrolysate (SPH), with 95 % reduced phenolic content, was studied for its protective effects against oxidative stress in intestinal cells (Caco-2). Produced via alcalase hydrolysis, SPH's molecular weight, amino acid composition, a...

Integration of multi-omics data and machine learning to identify antioxidant biomarkers in type 1 diabetes.

Free radical biology & medicine
The identification of biomarkers for early diagnosis and monitoring the progression of Type 1 Diabetes (T1DM) is essential for improving disease management. This study integrates multi-omics data with machine learning to identify antioxidant stress p...

AI-Driven Design and Development of Nontoxic DYRK1A Inhibitors.

Journal of medicinal chemistry
Dual-specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A) is implicated in several human diseases, including DYRK1A syndrome, cancer, and neurodegenerative disorders such as Alzheimer's disease, making it a relevant therapeutic target. I...

Amelioration of Chronic Ethanol Administration-Induced Learning and Memory Impairments by High-Intensity Interval Training (HIIT) and Ritalin.

Brain and behavior
OBJECTIVES: The current study aimed to investigate the impacts of 8-week high-intensity interval training (HIIT) and Ritalin (RIT), alone and in combination, on cognitive functions and hippocampal oxidative parameters following chronic ethanol consum...

Single and Multi-Objective Optimization of the Red Pine Mushroom Lactarius deliciosus (Agaricomycetes) Extraction Conditions Using Artificial Intelligence Methods and Biological Activities of Optimized Extracts.

International journal of medicinal mushrooms
In this study, the biological activities of Lactarius deliciosus were determined. Experimental studies were carried out using a soxhlet device, in the range of 40-70°C extraction temperature, 3-9 h extraction time and 0.5-2 mg/ ml extraction conditio...

Elettaria cardamomum essential oil; immunomodulatory, antioxidant, and anti-inflammatory effects for controlling acute Toxoplasma gondii infection.

Tropical biomedicine
The present study was conducted to investigate the immunomodulatory and anti-inflammatory effects of Elettaria cardamomum essential oil (ECEO) for the control of acute Toxoplasma gondii infection. The effect of ECEO on T. gondii tachyzoites was measu...

IGF-1 stabilizes goat sperm mitochondrial transmembrane potential and reduces dna fragmentation.

Cryo letters
BACKGROUND: Antioxidant present in sperm cells protects them from oxidative damage. However, sperm are more susceptible to peroxidative damages due to the loss of these enzymes during cryopreservation and their survival and fertility may be compromis...

Kidney dysfunction and oxidative stress in doxorubicin-induced nephrotic rat: Protective role of sesame oil.

Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia
Doxorubicin (DOX) is an antineoplastic agent which it's clinical use has been limited due to its major side effects including cardiotoxicity and nephrotic syndrome. Sesame oil (SO) is an important edible oil with many pharmacologic effects. The aim o...

[Separation and screening of antioxidant peptides from based on nano flow liquid chromatography].

Se pu = Chinese journal of chromatography
As a rich source of high activity antioxidant peptides, is a key marine natural product with a high processing value. Due to the high complexity of fish tissues, high recovery extraction and high efficiency screening of the active antioxidant peptid...