OBJECTIVE: We aimed to develop a prediction model for diagnosing severe aortic stenosis (AS) using computed tomography (CT) radiomics features of aortic valve calcium (AVC) and machine learning (ML) algorithms.
BACKGROUND: This study evaluated the performance of a machine learning (ML) algorithm in predicting outcomes of surgical aortic valve replacement (SAVR).
Clinical research in cardiology : official journal of the German Cardiac Society
Jun 24, 2020
BACKGROUND: Currently, patient selection in TAVI is based upon a multidisciplinary heart team assessment of patient comorbidities and surgical risk stratification. In an era of increasing need for precision medicine and quickly expanding TAVI indicat...
BACKGROUND: There is a lack of studies investigating the heterogeneity of patients with aortic stenosis (AS). We explored whether cluster analysis identifies distinct subgroups with different prognostic significances in AS.
Journal of the American Heart Association
Mar 21, 2020
Background Severe, symptomatic aortic stenosis (AS) is associated with poor prognoses. However, early detection of AS is difficult because of the long asymptomatic period experienced by many patients, during which screening tools are ineffective. The...
Journal of medical engineering & technology
Feb 24, 2020
In this study, we describe the design, fabrication and computational testing of a new prosthetic device for aortic valve replacement. The device is an active stent composed of a silicone rubber during initial prototyping, with adaptation towards a hy...
Biomedical repositories such as the UK Biobank provide increasing access to prospectively collected cardiac imaging, however these data are unlabeled, which creates barriers to their use in supervised machine learning. We develop a weakly supervised ...
Journal of infection in developing countries
Apr 30, 2019
Streptococcus gallolyticus (S. gallolyticus) bacteremia is commonly associated with endocarditis and diseases of gastrointestinal tract, especially with colorectal carcinoma. On the other side, it is rarely connected to liver disease, especially alco...
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