AIMC Topic: Apoptosis
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Protective effect of aspirin against mitomycin C-induced carcinogenicity, assessed by the test for detection of epithelial tumor clones (warts) in Drosophila melanogaster.
Drug and chemical toxicology
Dec 27, 2017
The present study assessed the protective effect of aspirin against carcinogenicity induced by mitomycin C (MMC) by the test for detection of warts/epithelial tumor clones in Drosophila melanogaster. Larvae were treated with different concentrations ...
Peanut testa extracts possessing histone deacetylase inhibitory activity induce apoptosis in cholangiocarcinoma cells.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Dec 27, 2017
Previous studies demonstrated that peanut testa extracts (KK4 and ICG15042) containing natural histone deacetylase (HDAC) inhibitors inhibited the growth of several human cancer cell lines via apoptosis induction. The aims of this study were to inves...
Chemical characterization, antioxidant, genotoxic and in vitro cytotoxic activity assessment of Juniperus communis var. saxatilis.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Dec 26, 2017
Chemical composition and antioxidative, genotoxic and cytotoxic potential of essential oil (EO) and post-distillation waste (PDW) of Serbian Juniperus communis L. var. saxatilis Pall. was studied in human lung carcinoma (A549) and normal lung fibrobl...
Male
Cell Line, Tumor
Antioxidants
Plant Extracts
Rats
Apoptosis
Cell Line
Antineoplastic Agents, Phytogenic
Chromatography, Liquid
Humans
Female
Animals
Mutagens
Drug Screening Assays, Antitumor
Cell Division
Tandem Mass Spectrometry
G2 Phase
Gas Chromatography-Mass Spectrometry
Juniperus
Doxorubicin
Gas chromatography-mass spectrometry metabolomic study of lipopolysaccharides toxicity on rat basophilic leukemia cells.
Chemico-biological interactions
Dec 22, 2017
Lipopolysaccharide (LPS) can lead to uncontrollable cytokine production, fatal sepsis syndrome and depression/multiple organ failure, as pathophysiologic demonstration. Various toxic effects of LPS have been extensively reported, mainly on the toxici...
[In vitro Modulating Activity of aqueous extracts from American Plants on Chlorpyrifos-induced toxicity on Murine Splenocytes].
Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina)
Dec 21, 2017
BACKGROUND: Chlorpyrifos is an highly toxic pesticide, which can induce immunotoxicity with deleterious effects on health worldwide. On the other hand, American plants can provide derivatives with protective and immunostimulating activity. Thus, plan...
In vitro effects of virgin microplastics on fish head-kidney leucocyte activities.
Environmental pollution (Barking, Essex : 1987)
Dec 20, 2017
Microplastics are well-documented pollutants in the marine environment that result from production or fragmentation of larger plastic items. The knowledge about the direct effects of microplastics on immunity, including fish, is still very limited. W...
Serum Vitamin D Levels Affect Pathologic Complete Response in Patients Undergoing Neoadjuvant Systemic Therapy for Operable Breast Cancer.
Clinical breast cancer
Dec 11, 2017
INTRODUCTION: There has been increasing interest in the potential benefit of vitamin D in improving breast cancer outcome. Preclinical studies suggest that vitamin D enhances chemotherapy-induced cell death. We investigated the impact of serum vitami...
Ginsenoside Rg1 protects human renal tubular epithelial cells from lipopolysaccharide-induced apoptosis and inflammation damage.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas
Dec 11, 2017
Ginsenoside Rg1, one of the most notable active components of Panax ginseng, has been widely reported to exert anti-inflammatory actions. This study aimed to reveal whether ginsenoside Rg1 also exhibits beneficial roles against lipopolysaccharide (LP...
Proto-Oncogene Proteins c-akt
Analysis of Variance
Kidney Tubules
Cell Migration Assays
Ginsenosides
Protective Agents
Blotting, Western
Anti-Inflammatory Agents
Phosphatidylinositol 3-Kinases
Nephritis
Lipopolysaccharides
Cytokines
Humans
Cell Line
Reproducibility of Results
Reactive Oxygen Species
Enzyme-Linked Immunosorbent Assay
Epithelial Cells
Apoptosis
Cell Survival
Oleanolic acid protects against pathogenesis of atherosclerosis, possibly via FXR-mediated angiotensin (Ang)-(1-7) upregulation.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Dec 8, 2017
Atherosclerosis, the leading cause of cardiovascular diseases in the world, is a chronic inflammatory disorder characterized by the dysfunction of arteries. Oleanolic acid (OA) is a bioactive nature product which exists in various plants and herbs. P...
Azithromycin and Chloramphenicol Diminish Neutrophil Extracellular Traps (NETs) Release.
International journal of molecular sciences
Dec 8, 2017
Neutrophils are one of the first cells to arrive at the site of infection, where they apply several strategies to kill pathogens: degranulation, respiratory burst, phagocytosis, and release of neutrophil extracellular traps (NETs). Antibiotics have a...
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