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Bacteremia

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Clinical evaluation of a multiplex droplet digital PCR for diagnosing suspected bloodstream infections: a prospective study.

Frontiers in cellular and infection microbiology
BACKGROUND: Though droplet digital PCR (ddPCR) has emerged as a promising tool for early pathogen detection in bloodstream infections (BSIs), more studies are needed to support its clinical application widely due to different ddPCR platforms with dis...

Mandatory surveillance of bacteremia conducted by automated monitoring.

Frontiers in public health
Except for a few countries, comprehensive all-cause surveillance for bacteremia is not part of mandatory routine public health surveillance. We argue that time has come to include automated surveillance for bacteremia in the national surveillance sys...

High procalcitonin level is related to blood stream infections, gram-negative pathogens, and ICU admission in infections of adult febrile cancer patients.

Journal of the Egyptian National Cancer Institute
BACKGROUND: Blood stream infection (BSI) represent a life-threatening condition. Thus, we aimed to investigate the role of procalcitonin (PCT) and C-reactive protein (CRP) tests in adult febrile patients with BSI and other clinical infections in hosp...

Advances in diagnosis and prognosis of bacteraemia, bloodstream infection, and sepsis using machine learning: A comprehensive living literature review.

Artificial intelligence in medicine
BACKGROUND: Blood-related infections are a significant concern in healthcare. They can lead to serious medical complications and even death if not promptly diagnosed and treated. Throughout time, medical research has sought to identify clinical facto...

Machine learning and clinician predictions of antibiotic resistance in Enterobacterales bloodstream infections.

The Journal of infection
BACKGROUND: Patients with Gram-negative bloodstream infections are at risk of serious adverse outcomes without active treatment, but identifying who has antimicrobial resistance (AMR) to target empirical treatment is challenging.

Utilizing artificial intelligence and cellular population data for timely identification of bacteremia in hospitalized patients.

International journal of medical informatics
BACKGROUND: Bacteremia is a critical condition with high mortality that requires prompt detection to prevent progression to life-threatening sepsis. Traditional diagnostic approaches, such as blood cultures, are time-consuming. This limitation has en...

Machine learning-based prediction model for patients with recurrent Staphylococcus aureus bacteremia.

BMC medical informatics and decision making
BACKGROUND: Staphylococcus aureus bacteremia (SAB) remains a significant contributor to both community-acquired and healthcare-associated bloodstream infections. SAB exhibits a high recurrence rate and mortality rate, leading to numerous clinical tre...

Machine learning-based prognostic model for bloodstream infections in hematological malignancies using Th1/Th2 cytokines.

BMC infectious diseases
OBJECTIVE: Bloodstream infection (BSI) is a significant cause of mortality in patients with hematologic malignancies(HMs), particularly amid rising antibiotic resistance. This study aimed to analyze pathogen distribution, drug-resistance patterns and...

Utilising routinely collected clinical data through time series deep learning to improve identification of bacterial bloodstream infections: a retrospective cohort study.

The Lancet. Digital health
BACKGROUND: Blood cultures are the gold standard for diagnosing bacterial bloodstream infections, but test results are only available 24-48 h after sampling. We aimed to develop and evaluate models using health-care data to predict bloodstream infect...