Tandem mass spectrometry (MS/MS)-based phosphoproteomics is a powerful technology for global phosphorylation analysis. However, applying four computational pipelines to a typical mass spectrometry (MS)-based phosphoproteomic dataset from a human canc...
Cancer diagnosis, prognosis, and therapy response predictions from tissue specimens highly depend on the phenotype and topological distribution of constituting histological entities. Thus, adequate tissue representations for encoding histological ent...
International journal of environmental research and public health
Oct 14, 2021
With the development of information and technology, especially with the boom in big data, healthcare support systems are becoming much better. Patient data can be collected, retrieved, and stored in real time. These data are valuable and meaningful f...
Training a neural network with a large labeled dataset is still a dominant paradigm in computational histopathology. However, obtaining such exhaustive manual annotations is often expensive, laborious, and prone to inter and intra-observer variabilit...
IMPORTANCE: Machine learning could be used to predict the likelihood of diagnosis and severity of illness. Lack of COVID-19 patient data has hindered the data science community in developing models to aid in the response to the pandemic.
We propose weakly supervised training schemes to train end-to-end cell segmentation networks that only require a single point annotation per cell as the training label and generate a high-quality segmentation mask close to those fully supervised meth...
Automatic methods for feature extraction, volumetry, and morphometric analysis in clinical neuroscience typically operate on images obtained with magnetic resonance (MR) imaging equipment. Although CT scans are less expensive to acquire and more wide...
Named entity recognition (NER) is one fundamental task in the natural language processing (NLP) community. Supervised neural network models based on contextualized word representations can achieve highly-competitive performance, which requires a larg...
Long-read sequencing enables variant detection in genomic regions that are considered difficult-to-map by short-read sequencing. To fully exploit the benefits of longer reads, here we present a deep learning method NanoCaller, which detects SNPs usin...
Cosegmentation is a newly emerging computer vision technique used to segment an object from the background by processing multiple images at the same time. Traditional plant phenotyping analysis uses thresholding segmentation methods which result in h...
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