AIMC Topic: Bilirubin

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Development of an equation to predict delta bilirubin levels using machine learning.

Clinica chimica acta; international journal of clinical chemistry
OBJECTIVE: Delta bilirubin (albumin-covalently bound bilirubin) may provide important clinical utility in identifying impaired hepatic excretion of conjugated bilirubin, but it cannot be measured in real-time for diagnostic purposes in clinical labor...

Machine learning-causal inference based on multi-omics data reveals the association of altered gut bacteria and bile acid metabolism with neonatal jaundice.

Gut microbes
Early identification of neonatal jaundice (NJ) appears to be essential to avoid bilirubin encephalopathy and neurological sequelae. The interaction between gut microbiota and metabolites plays an important role in early life. It is unclear whether th...

Machine learning-based model for predicting tumor recurrence after interventional therapy in HBV-related hepatocellular carcinoma patients with low preoperative platelet-albumin-bilirubin score.

Frontiers in immunology
INTRODUCTION: This study aimed to develop a prognostic nomogram for predicting the recurrence-free survival (RFS) of hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) patients with low preoperative platelet-albumin-bilirubin (PALBI) scor...

Machine Learning to Improve Accuracy of Transcutaneous Bilirubinometry.

Neonatology
INTRODUCTION: This study aimed to develop models for predicting total serum bilirubin by correcting errors of transcutaneous bilirubin using machine learning based on neonatal biomarkers that could affect spectrophotometric measurements of tissue bil...

Upper gastrointestinal haemorrhage patients' survival: A causal inference and prediction study.

European journal of clinical investigation
BACKGROUND: Upper gastrointestinal (GI) bleeding is a common medical emergency. This study aimed to develop models to predict critically ill patients with upper GI bleeding in-hospital and 30-day survival, identify the correlation factor and infer th...

Personalising monitoring for chemotherapy patients through predicting deterioration in renal and hepatic function.

Cancer medicine
BACKGROUND: In those receiving chemotherapy, renal and hepatic dysfunction can increase the risk of toxicity and should therefore be monitored. We aimed to develop a machine learning model to identify those patients that need closer monitoring, enabl...

Diagnosis of liver diseases based on artificial intelligence.

Biotechnology & genetic engineering reviews
Due to a series of problems in the diagnosis of liver disease, the mortality rate of liver disease patients is very high. Therefore, it is necessary for doctors and researchers to find a more effective non-invasive diagnostic method to meet clinical ...

Employing biochemical biomarkers for building decision tree models to predict bipolar disorder from major depressive disorder.

Journal of affective disorders
BACKGROUND: Conventional biochemical parameters may have predictive values for use in clinical identification between bipolar disorder (BD) and major depressive disorder (MDD).

Detecting acute bilirubin encephalopathy in neonates based on multimodal MRI with deep learning.

Pediatric research
BACKGROUND: Differentiating acute bilirubin encephalopathy (ABE) from non-ABE in neonates with hyperbilirubinemia (HB) from routine magnetic resonance imaging (MRI) is extremely challenging since both conditions demonstrate similar T1 hyperintensitie...