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Bioengineering

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Dynamic Metabolomics for Engineering Biology: Accelerating Learning Cycles for Bioproduction.

Trends in biotechnology
Metabolomics is a powerful tool to rationally guide the metabolic engineering of synthetic bioproduction pathways. Current reports indicate great potential to further develop metabolomics-directed synthetic bioproduction. Advanced mass metabolomics m...

Discovering the hidden messages within cell trajectories using a deep learning approach for in vitro evaluation of cancer drug treatments.

Scientific reports
We describe a novel method to achieve a universal, massive, and fully automated analysis of cell motility behaviours, starting from time-lapse microscopy images. The approach was inspired by the recent successes in application of machine learning for...

Grasping with kirigami shells.

Science robotics
The ability to grab, hold, and manipulate objects is a vital and fundamental operation in biological and engineering systems. Here, we present a soft gripper using a simple material system that enables precise and rapid grasping, and can be miniaturi...

Establishing an Octopus Ecosystem for Biomedical and Bioengineering Research.

Journal of visualized experiments : JoVE
Many developments in biomedical research have been inspired by discovering anatomical and cellular mechanisms that support specific functions in different species. The octopus is one of these exceptional animals that has given scientists new insights...

Vital signal sensing and manipulation of a microscale organ with a multifunctional soft gripper.

Science robotics
Soft grippers that incorporate functional materials are important in the development of mechanically compliant and multifunctional interfaces for both sensing and stimulating soft objects and organisms. In particular, the capability for firm and deli...

Combining novel technologies with interdisciplinary basic research to enhance horticultural crops.

The Plant journal : for cell and molecular biology
Horticultural crops mainly include fruits, vegetables, ornamental trees and flowers, and tea trees (Melaleuca alternifolia). They produce a variety of nutrients for the daily human diet in addition to the nutrition provided by staple crops, and some ...

Synthetic growth by self-lubricated photopolymerization and extrusion inspired by plants and fungi.

Proceedings of the National Academy of Sciences of the United States of America
Many natural organisms, such as fungal hyphae and plant roots, grow at their tips, enabling the generation of complex bodies composed of natural materials as well as dexterous movement and exploration. Tip growth presents an exemplary process by whic...

Electrospray mode discrimination with current signal using deep convolutional neural network and class activation map.

Scientific reports
The electrospray process has been extensively applied in various fields, including energy, display, sensor, and biomedical engineering owing to its ability to generate of functional micro/nanoparticles. Although the mode of the electrospray process h...