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Biopsy

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Assessing the diagnostic accuracy of ChatGPT-4 in the histopathological evaluation of liver fibrosis in MASH.

Hepatology communications
BACKGROUND: Large language models like ChatGPT have demonstrated potential in medical image interpretation, but their efficacy in liver histopathological analysis remains largely unexplored. This study aims to assess ChatGPT-4-vision's diagnostic acc...

Evaluation of minor labial salivary gland focus score in Sjögren's disease using deep learning: a tool for more efficient diagnosis and future tissue biomarker discovery.

Journal of autoimmunity
BACKGROUND: Sjögren's Disease (SjD) is histopathologically characterized by focal sialadenitis in minor labial salivary gland biopsies (mLSGB), which is evaluated by utilizing the focus score (FS). Focus score ≥1 identification is a critical step of ...

Intelligent Bi-Dimensional Skin Biopsies of Rheumatoid Arthritis Based on Raman Spectral Imaging and Machine Learning.

Analytical chemistry
Rheumatoid arthritis (RA) is one of the most common autoimmune diseases worldwide, characterized by its progressive and irreversible nature. Early diagnosis is crucial for delaying disease progression and optimizing treatment strategies. Existing dia...

Machine learning allows robust classification of lung neoplasm tissue using an electronic biopsy through minimally-invasive electrical impedance spectroscopy.

Scientific reports
New bronchoscopy techniques like radial probe endobronchial ultrasound have been developed for real-time sampling characterization, but their use is still limited. This study aims to use classification algorithms with minimally invasive electrical im...

Effective reduction of unnecessary biopsies through a deep-learning-assisted aggressive prostate cancer detector.

Scientific reports
Despite being one of the most prevalent cancers, prostate cancer (PCa) shows a significantly high survival rate, provided there is timely detection and treatment. Currently, several screening and diagnostic tests are required to be carried out in ord...

Artificial intelligence-aided optical biopsy improves the diagnosis of esophageal squamous neoplasm.

World journal of gastroenterology
BACKGROUND: Early detection of esophageal squamous neoplasms (ESN) is essential for improving patient prognosis. Optical diagnosis of ESN remains challenging. Probe-based confocal laser endomicroscopy (pCLE) enables accurate histological observation...

Rapid diagnosis of membranous nephropathy based on kidney tissue Raman spectroscopy and deep learning.

Scientific reports
Membranous nephropathy (MN) is one of the most common glomerular diseases. Although the diagnostic method based on serum PLA2R antibodies has gradually been applied in clinical practice, only 52-86% of PLA2R-associated MN patients show positive anti-...

Neural network analysis as a novel skin outcome in a trial of belumosudil in patients with systemic sclerosis.

Arthritis research & therapy
BACKGROUND: The modified Rodnan skin score (mRSS), a measure of systemic sclerosis (SSc) skin thickness, is agnostic to inflammation and vasculopathy. Previously, we demonstrated the potential of neural network-based digital pathology applied to SSc ...

Artificial intelligence-enhanced interpretation of kidney transplant biopsy: focus on rejection.

Current opinion in organ transplantation
PURPOSE OF REVIEW: The objective of this review is to provide an update on the application of artificial intelligence (AI) for the histological interpretation of kidney transplant biopsies.

Enhancing basal cell carcinoma classification in preoperative biopsies via transfer learning with weakly supervised graph transformers.

BMC medical imaging
BACKGROUND: Basal cell carcinoma (BCC) is the most common skin cancer, placing a significant burden on healthcare systems globally. Developing high-precision automated diagnostics requires large annotated datasets, which are costly and difficult to o...