AIMC Topic: Biopsy

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Multi-stain deep learning prediction model of treatment response in lupus nephritis based on renal histopathology.

Kidney international Dec 27, 2024
The response of the kidney after induction treatment is one of the determinants of prognosis in lupus nephritis, but effective predictive tools are lacking. Here, we sought to apply deep learning approaches on kidney biopsies for treatment response p...
Biopsy Proteinuria Mycophenolic Acid Cyclophosphamide Glomerular Filtration Rate Immunosuppressive Agents Predictive Value of Tests Lupus Nephritis Humans Retrospective Studies Middle Aged Female Deep Learning Young Adult Kidney Adult Treatment Outcome Male
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Diagnostic accuracy of texture analysis applied to T- and T-Relaxation maps for liver fibrosis classification via machine-learning algorithms with liver histology as reference standard.

European journal of radiology Dec 20, 2024
OBJECTIVES: To explore texture analysis' ability on T and T relaxation maps to classify liver fibrosis into no-to-mild liver fibrosis (nmF) versus severe fibrosis (sF) group using machine learning algorithms and histology as reference standard.
Humans Retrospective Studies Female Aged Adult Male Middle Aged Severity of Illness Index Image Interpretation, Computer-Assisted Reference Standards Elasticity Imaging Techniques Echo-Planar Imaging Liver ROC Curve Principal Component Analysis Liver Cirrhosis Area Under Curve Support Vector Machine Biopsy Magnetic Resonance Imaging
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Prediction of mucinous adenocarcinoma in colorectal cancer with mucinous components detected in preoperative biopsy diagnosis.

Abdominal radiology (New York) Dec 12, 2024
OBJECTIVES: Endoscopic biopsy diagnosis for the preoperative assessment of mucinous components in patients with colorectal cancer is limited. This study investigated a radiomics model and established an explainable prediction model by using machine l...
Humans Machine Learning Retrospective Studies Female Diagnosis, Differential Predictive Value of Tests Biopsy Aged Preoperative Care Adenocarcinoma, Mucinous Colorectal Neoplasms Male Middle Aged
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Stress testing deep learning models for prostate cancer detection on biopsies and surgical specimens.

The Journal of pathology Dec 11, 2024
The presence, location, and extent of prostate cancer is assessed by pathologists using H&E-stained tissue slides. Machine learning approaches can accomplish these tasks for both biopsies and radical prostatectomies. Deep learning approaches using co...
Prostatic Neoplasms Biopsy Prostatectomy Humans Neural Networks, Computer Male Deep Learning
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Quantitative fibrosis identifies biliary tract involvement and is associated with outcomes in pediatric autoimmune liver disease.

Hepatology communications Dec 11, 2024
BACKGROUND: Children with autoimmune liver disease (AILD) may develop fibrosis-related complications necessitating a liver transplant. We hypothesize that tissue-based analysis of liver fibrosis by second harmonic generation (SHG) microscopy with art...
Autoimmune Diseases Hepatitis, Autoimmune Cholangitis, Sclerosing Liver Cirrhosis Liver Biopsy Liver Transplantation Male Adolescent Child, Preschool Child Prognosis Female Young Adult Humans Artificial Intelligence
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Let it shine: Autofluorescence of Papanicolaou-stain improves AI-based cytological oral cancer detection.

Computers in biology and medicine Dec 10, 2024
BACKGROUND AND OBJECTIVES: Oral cancer is a global health challenge. The disease can be successfully treated if detected early, but the survival rate drops significantly for late stage cases. There is a growing interest in a shift from the current st...
Image Interpretation, Computer-Assisted Datasets as Topic Optical Imaging Mouth Mucosa Multimodal Imaging Biopsy Mouth Neoplasms Microscopy Humans Adult Deep Learning Papanicolaou Test Early Detection of Cancer
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Comparison of deep learning schemes in grading non-alcoholic fatty liver disease using B-mode ultrasound hepatorenal window images with liver biopsy as the gold standard.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) Dec 2, 2024
BACKGROUND/INTRODUCTION: To evaluate the performance of pre-trained deep learning schemes (DLS) in hepatic steatosis (HS) grading of Non-Alcoholic Fatty Liver Disease (NAFLD) patients, using as input B-mode US images containing right kidney (RK) cort...
Humans Image Processing, Computer-Assisted Kidney Liver Biopsy Non-alcoholic Fatty Liver Disease Middle Aged Female Reference Standards Deep Learning Aged Ultrasonography Adult ROC Curve Male
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Pediatric Liver Transplant Pathology: An Update and Practical Consideration.

Surgical pathology clinics Nov 28, 2024
This review provides a summary of the diagnostic approach to pediatric liver transplantation (LT) pathology. It emphasizes the pathologic features of T-cell-mediated rejection, the most common finding on liver allograft biopsies, and discusses other ...
Liver Graft Rejection Biopsy Liver Transplantation Humans Child
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Deep learning-accelerated T2WI of the prostate for transition zone lesion evaluation and extraprostatic extension assessment.

Scientific reports Nov 25, 2024
This bicenter retrospective analysis included 162 patients who had undergone prostate biopsy following prebiopsy MRI, excluding those with PCa identified only in the peripheral zone (PZ). DLR T2WI achieved a 69% reduction in scan time relative to TSE...
Prostatic Neoplasms Prostate Biopsy Humans Middle Aged Retrospective Studies Deep Learning Aged ROC Curve Male Magnetic Resonance Imaging
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Clinical validation of an AI-based pathology tool for scoring of metabolic dysfunction-associated steatohepatitis.

Nature medicine Nov 4, 2024
Metabolic dysfunction-associated steatohepatitis (MASH) is a major cause of liver-related morbidity and mortality, yet treatment options are limited. Manual scoring of liver biopsies, currently the gold standard for clinical trial enrollment and endp...
Biopsy Non-alcoholic Fatty Liver Disease Male Humans Middle Aged Artificial Intelligence Fatty Liver Female Liver Reproducibility of Results Adult
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