AIMC Topic: Biphenyl Compounds

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Sacubitril/Valsartan in an Elderly Patient with Heart Failure: A Case Report.

Cardiology Dec 21, 2017
Sacubitril/valsartan has recently been approved for the treatment of heart failure with reduced ejection fraction. Given its recent introduction in the armamentarium for the treatment of heart failure (HF), "field-practice" evidence is required to de...
Valsartan Angiotensin Receptor Antagonists Tetrazoles Heart Failure Aminobutyrates Biphenyl Compounds Humans Aged, 80 and over Male Stroke Volume Echocardiography Drug Combinations Heart Ventricles
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Innovative spectrophotometric methods for simultaneous estimation of the novel two-drug combination: Sacubitril/Valsartan through two manipulation approaches and a comparative statistical study.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy Dec 17, 2017
Different innovative spectrophotometric methods were introduced for the first time for simultaneous quantification of sacubitril/valsartan in their binary mixture and in their combined dosage form without prior separation through two manipulation app...
Angiotensin Receptor Antagonists Tetrazoles Statistics as Topic Spectrophotometry Aminobutyrates Biphenyl Compounds Valsartan Drug Combinations Tablets
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Phenolic constituents of Pulicaria undulata (L.) C.A. Mey. sub sp. undulata (Asteraceae): Antioxidant protective effects and chemosystematic significances.

Journal of food and drug analysis Dec 22, 2016
One new naturally isoflavone compound, 5,7,2',3',4' penta hydroxyl isoflavone-4'-O-β-glucopyranoside (1) was isolated from the aqueous methanol extract (AME) of Pulicaria undulata subsp. undulata, together with seven known compounds: kaempferol (2), ...
Animals Pulicaria Mice Antioxidants Biphenyl Compounds Picrates
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Analytical Method for the Detection of Residual Active Ingredients Found in Neutralized Suspensions of Antimicrobial Products.

Journal of AOAC International Nov 10, 2016
An analytical method for determining the presence and levels of residual active ingredients found in neutralized suspensions of phenolic and quaternary ammonium salt-based antimicrobial products was developed using solid-phase extraction in combinati...
Phenols Anti-Infective Agents Benzalkonium Compounds Culture Media Tandem Mass Spectrometry Chromatography, Ion Exchange Lipids Sodium Hypochlorite Dichlorophen Biphenyl Compounds Thiosulfates
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Composition of Asarum heterotropoides var. mandshuricum radix oil from different extraction methods and activities against human body odor-producing bacteria.

Journal of food and drug analysis Jun 21, 2016
In this study, oils from Asarum heterotropoides were extracted by traditional solvent extraction and supercritical CO (SC-CO) extraction methods and their antioxidant activities along with antimicrobial and inhibitory activities against five human bo...
Humans Bacteria Odorants Human Body Biphenyl Compounds Picrates Asarum
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Determination of DPPH free radical scavenging activity: application of artificial neural networks.

Food chemistry Aug 12, 2015
A new computational approach for the determination of 2,2-diphenyl-1-picrylhydrazyl free radical scavenging activity (DPPH-RSA) in food is reported, based on the concept of machine learning. Trolox standard was mix with DPPH at different concentratio...
Free Radical Scavengers Neural Networks, Computer Biphenyl Compounds Picrates
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Combination of counterpropagation artificial neural networks and antioxidant activities for comprehensive evaluation of associated-extraction efficiency of various cyclodextrins in the traditional Chinese formula Xue-Zhi-Ning.

Journal of pharmaceutical and biomedical analysis Aug 12, 2015
Xue-Zhi-Ning (XZN) is a widely used traditional Chinese medicine formula to treat hyperlipidemia. Recently, cyclodextrins (CDs) have been extensively used to minimize problems relative to medicine bioavailability, such as low solubility and poor stab...
Neural Networks, Computer Antioxidants Drugs, Chinese Herbal Cyclodextrins Technology, Pharmaceutical Chemistry, Pharmaceutical Chromatography, High Pressure Liquid Hydroxyl Radical Lipid Peroxidation Biphenyl Compounds Picrates
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Overview of the Biological Activities of a Methanol Extract from Wild Red Belt Conk, Fomitopsis pinicola (Agaricomycetes), Fruiting Bodies from Central Italy.

International journal of medicinal mushrooms Jan 1, 2018
Fomitopsis pinicola (Sw.) P. Karst. (Fomitopsidaceae) is a medicinal mushroom with a variety of healthy properties. In this study we tested the radical scavenging activity and antimicrobial and anticancer potential of methanol extracts of F. pinicola...
Fruiting Bodies, Fungal Flavonoids Coriolaceae Phenols Methanol Microbial Sensitivity Tests Humans Picrates Antifungal Agents HT29 Cells Agaricales Cell Proliferation Antineoplastic Agents Chemical Fractionation Apoptosis Phylogeny THP-1 Cells Free Radical Scavengers Cell Survival Biphenyl Compounds
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RESEARCH ON EXTRACTION TECHNOLOGY, ANTIBACTERIAL AND ANTIOXIDANT ACTIVITY OF ETHANOL EXTRACT FROM LEAVES OF ABUTILON THEOPHRASTI MEDIC.

Acta poloniae pharmaceutica May 1, 2017
This paper described the extraction procedure and determination method for the total flavonoids in ethanol extract from the leaves of Abutilon theophrasti Medic., and evaluated antibacterial and antioxidant activity. Maximum extraction yield was achi...
Anti-Bacterial Agents Microbial Sensitivity Tests Microbial Viability Antioxidants Plant Extracts Escherichia coli Solvents Benzothiazoles Sulfonic Acids Hydroxyl Radical Phytotherapy Malvaceae Staphylococcus aureus Plant Leaves Ethanol Plants, Medicinal Dose-Response Relationship, Drug Biphenyl Compounds Picrates
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DEVELOPMENT AND VALIDATION OF HPLC ANALYTICAL METHODS USED-FOR DETERMINATION OF ASSAY, CONTENT UNIFORMITY AND DISSOLUTION OF IMMEDIATE RELEASE CANDESARTAN CILEXETIL 32 MG TABLETS.

Acta poloniae pharmaceutica Mar 1, 2017
New analytical methods have been developed and validated on high performance liquid chromatography (HPLC) to assess the assay, content uniformity and dissolution of immediate release candesartan cilexetil 32 mg tablets. Method development studies wer...
Angiotensin II Type 1 Receptor Blockers Buffers Chemistry, Pharmaceutical Temperature Tetrazoles Benzimidazoles Chromatography, High Pressure Liquid Solvents Solubility Drug Compounding Reproducibility of Results Drug Liberation Linear Models Biphenyl Compounds Limit of Detection Hydrogen-Ion Concentration Tablets
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