AIMC Topic: Caffeic Acids

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Comprehensive machine learning models for predicting therapeutic targets in type 2 diabetes utilizing molecular and biochemical features in rats.

Frontiers in endocrinology May 24, 2024
INTRODUCTION: With the increasing prevalence of type 2 diabetes mellitus (T2DM), there is an urgent need to discover effective therapeutic targets for this complex condition. Coding and non-coding RNAs, with traditional biochemical parameters, have s...
Male Diabetes Mellitus, Type 2 Insulin Resistance Machine Learning Biomarkers Animals Quercetin Caffeic Acids Rats, Sprague-Dawley Liver Diabetes Mellitus, Experimental Rats Hypoglycemic Agents
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Naturally occurring caffeic acid phenethyl ester from chestnut honey-based propolis and virtual screening towards DYRK1A.

Natural product research Feb 1, 2024
Neurodegenerative diseases (NDDs) are disorders with dysfunction and ongoing loss of neurons, glial cells and the neural networks in the brain and spinal cord. DYRK1A protein was reported to modulate to the cytoskeletal fraction in human and mouse br...
Protein Serine-Threonine Kinases Propolis Molecular Structure Mice Protein-Tyrosine Kinases Caffeic Acids Dyrk Kinases Phenylethyl Alcohol Humans Chromatography, High Pressure Liquid Animals Tandem Mass Spectrometry Molecular Docking Simulation Honey
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Characterization of Polyphenolic Content in the Aquatic Plants Ruppia cirrhosa and Ruppia maritima -A Source of Nutritional Natural Products.

Molecules (Basel, Switzerland) Dec 22, 2017
Herein, the polyphenolic content in extracts of (Petagna) Grande and L.was fully characterized for the first time. High amounts of the main compound chicoric acid () (≤30.2 ± 4.3 mg/g) were found in both species. In addition, eight flavonoids, nam...
Flavonoids Aquatic Organisms Seasons Biphenyl Compounds Magnetic Resonance Spectroscopy Plant Extracts Picrates Alismatales Biological Products Succinates Species Specificity Antioxidants Polyphenols Caffeic Acids
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A Combination of Coffee Compounds Shows Insulin-Sensitizing and Hepatoprotective Effects in a Rat Model of Diet-Induced Metabolic Syndrome.

Nutrients Dec 22, 2017
Since coffee may help to prevent the development of metabolic syndrome (MetS), we aimed to evaluate the short- and long-term effects of a coffee-based supplement on different features of diet-induced MetS. In this study, 24 Sprague Dawley rats were d...
Caffeic Acids Carbon-13 Magnetic Resonance Spectroscopy Dietary Sucrose Alkaloids Diterpenes Liver Diet, High-Fat Lipids Coffea Non-alcoholic Fatty Liver Disease Disease Models, Animal Metabolic Syndrome Dietary Supplements Seeds Rats, Sprague-Dawley Cytokines Animals Blood Glucose Insulin Time Factors Insulin Resistance
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Enzymatic preparation of "functional oil" rich in feruloylated structured lipids with solvent-free ultrasound pretreatment.

Food chemistry Dec 19, 2017
In this study, a series of functional oils rich in feruloylated structured lipids (FSLs) was prepared by enzymatic transesterification of ethyl ferulate (EF) with triglycerides under ultrasound pretreatment. A conversion of more than 92.7% and contro...
Plant Oils Lipids Kinetics Antioxidants Lipase Triglycerides Caffeic Acids Fatty Acids Esterification Solvents Ultrasonics
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The allelopathic effect and safety evaluation of 3,4-Dihydroxybenzalacetone on Microcystis aeruginosa.

Pesticide biochemistry and physiology Aug 14, 2017
Harmful algal blooms (HABs) has been a serious problem in recent years, because of large quantities of cyanobacterial in eutrophic water. We studied the effects of 3,4-Dihydroxybenzalacetone (DBL) and other four compounds (vanillic acid, ferulic acid...
Lipid Peroxidation Microcystis Dose-Response Relationship, Drug Harmful Algal Bloom Anti-Bacterial Agents Hydroxybenzoates Allelopathy Superoxides Animals Zebrafish Caffeic Acids
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