Journal of cardiothoracic and vascular anesthesia
38262805
OBJECTIVES: To investigate the effect of retrograde autologous priming (RAP) on coagulation function using rotation thromboelastometry (ROTEM) in patients undergoing valvular cardiac surgery.
Scandinavian journal of trauma, resuscitation and emergency medicine
29262829
BACKGROUND: Coagulopathy in traumatic brain injury (TBI) has been associated with poor neurological outcomes and higher in-hospital mortality. In general principle of trauma management, hypothermia should be prevented as it directly worsens coagulopa...
Studies in health technology and informatics
29726436
In this paper, we present a system that allows patients who require anticoagulation medicine an opportunity to independently manage their dosage concentration with the help of two machine learning algorithms. The basic idea is to predict the next dos...
European heart journal. Cardiovascular pharmacotherapy
31821482
AIMS: Most clinical risk stratification models are based on measurement at a single time-point rather than serial measurements. Artificial intelligence (AI) is able to predict one-dimensional outcomes from multi-dimensional datasets. Using data from ...
Journal of pharmacokinetics and pharmacodynamics
33651241
Quantitative systems pharmacology models are often highly complex and not amenable to further simulation and/or estimation analyses. Model-order reduction can be used to derive a mechanistically sound yet simpler model of the desired input-output rel...
Anticoagulant drugs are commonly prescribed to prevent hypercoagulable states in patients with venous thromboembolism. The choice of the most efficient anticoagulant and the appropriate dosage regimen remain a complex problem because of the intersubj...
The development of intelligent blood coagulation diagnoses is awaited to meet the current need for large clinical time-sensitive caseloads due to its efficient and automated diagnoses. Herein, a method is reported and validated to realize it through ...
Journal of thrombosis and haemostasis : JTH
36696218
Artificial Intelligence and machine-learning (ML) studies are increasingly populating the life science space and some have also started to integrate certain clinical decision support tasks. However, most of the activities within this space understand...
INTRODUCTION: Continuous renal replacement therapy (CRRT) is a prolonged continuous extracorporeal blood purification therapy to replace impaired renal function. Typically, CRRT therapy requires routine anticoagulation, but for patients at risk of bl...
BACKGROUND: Coagulation system is currently known associated with the development of ischemic stroke (IS). Thus, the current study is designed to identify diagnostic value of coagulation genes (CGs) in IS and to explore their role in the immune micro...