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Breast Neoplasms

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TopoTxR: A topology-guided deep convolutional network for breast parenchyma learning on DCE-MRIs.

Medical image analysis
Characterization of breast parenchyma in dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is a challenging task owing to the complexity of underlying tissue structures. Existing quantitative approaches, like radiomics and deep learning ...

Multiparametric MRI Radiomics With Machine Learning for Differentiating HER2-Zero, -Low, and -Positive Breast Cancer: Model Development, Testing, and Interpretability Analysis.

AJR. American journal of roentgenology
MRI radiomics has been explored for three-tiered classification of HER2 expression levels (i.e., HER2-zero, HER2-low, or HER2-positive) in patients with breast cancer, although an understanding of how such models reach their predictions is lacking. ...

A Multicenter Cohort Study on Ultrasound-based Deep Learning Nomogram for Predicting Post-Neoadjuvant Chemotherapy Axillary Lymph Node Status in Breast Cancer Patients.

Academic radiology
RATIONALE AND OBJECTIVES: The aim of this study was to evaluate the capability of an ultrasound (US)-based deep learning (DL) nomogram for predicting axillary lymph node (ALN) status after neoadjuvant chemotherapy (NAC) in breast cancer patients and ...

A support vector machine-based approach to guide the selection of a pseudo-reference region for brain PET quantification.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
A Support Vector Machine (SVM) based approach was developed to identify a pseudo-reference region for brain PET scans with the aim of reducing interscan and intersubject variability. By training a binary linear SVM classifier with PET datasets from t...

A systematic scoping review exploring variation in practice in specimen mammography for Intraoperative Margin Analysis in Breast Conserving Surgery and the role of artificial intelligence in optimising diagnostic accuracy.

European journal of radiology
PURPOSE: Specimen Mammography (SM) is commonly used in Breast Conserving Surgery (BCS) for intraoperative margin analysis. A systematic scoping review was conducted to identify sources of methodological variation in Specimen Mammography Interpretatio...

Spatially Informed Graph Structure Learning Extracts Insights from Spatial Transcriptomics.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Embeddings derived from cell graphs hold significant potential for exploring spatial transcriptomics (ST) datasets. Nevertheless, existing methodologies rely on a graph structure defined by spatial proximity, which inadequately represents the diversi...

Prediction of pathological complete response to chemotherapy for breast cancer using deep neural network with uncertainty quantification.

Medical physics
BACKGROUND: The I-SPY 2 trial is a national-wide, multi-institutional clinical trial designed to evaluate multiple new therapeutic drugs for high-risk breast cancer. Previous studies suggest that pathological complete response (pCR) is a viable indic...

CureMate: A clinical decision support system for breast cancer treatment.

International journal of medical informatics
BACKGROUND: Breast Cancer (BC) poses significant challenges in treatment decision-making. Multiple first treatment lines are currently available, determined by several patient-specific factors that need to be considered in the decision-making process...

Ensemble approach of deep learning models for binary and multiclass classification of histopathological images for breast cancer.

Pathology, research and practice
Breast cancer (BC) is the most frequently occurring cancer disease observed in women after lung cancer. Out of different stages, invasive ductal BC causes maximum deaths in women. In this work, three deep learning (DL) models such as Vision Transform...

Breast tumor segmentation using neural cellular automata and shape guided segmentation in mammography images.

PloS one
PURPOSE: Using computer-aided design (CAD) systems, this research endeavors to enhance breast cancer segmentation by addressing data insufficiency and data complexity during model training. As perceived by computer vision models, the inherent symmetr...