AIMC Topic: Case-Control Studies

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Risk factors and machine learning prediction models for intrahepatic cholestasis of pregnancy.

BMC pregnancy and childbirth
BACKGROUND: Intrahepatic cholestasis of pregnancy (ICP) is a liver disorder that occurs in the second and third trimesters of pregnancy and is associated with a significant risk of fetal complications, including premature birth and fetal death. In cl...

Deep learning based prediction of depression and anxiety in patients with type 2 diabetes mellitus using regional electronic health records.

International journal of medical informatics
BACKGROUND: Depression and anxiety are prevalent mental health conditions among individuals with type 2 diabetes mellitus (T2DM), who exhibit unique vulnerabilities and etiologies. However, existing approaches fail to fully utilize regional heterogen...

Machine Learning-Based Diagnosis of Chronic Subjective Tinnitus With Altered Cognitive Function: An Event-Related Potential Study.

Ear and hearing
OBJECTIVES: Due to the absence of objective diagnostic criteria, tinnitus diagnosis primarily relies on subjective assessments. However, its neuropathological features can be objectively quantified using electroencephalography (EEG). Despite the exis...

Machine learning-based assessment of morphometric abnormalities distinguishes bipolar disorder and major depressive disorder.

Neuroradiology
INTRODUCTION: Bipolar disorder (BD) and major depressive disorder (MDD) have overlapping clinical presentations which may make it difficult for clinicians to distinguish them potentially resulting in misdiagnosis. This study combined structural MRI a...

The status of serum 25(OH)D levels is related to breast cancer.

Cancer treatment and research communications
AIM: Breast cancer is the second most common cancer among women and the leading cause of cancer-related mortality in this population. Numerous factors have been identified as either risk factors or protective factors for breast cancer. However, the r...

Machine learning analysis of cervical balance in early-onset scoliosis post-growing rod surgery: a case-control study.

Scientific reports
We aimed to analyze the cervical sagittal alignment change following the growing rod treatment in early-onset scoliosis (EOS) and identify the risk factors of sagittal cervical imbalance after growing-rod surgery of machine learning. EOS patients fro...

Development of a multi-laboratory integrated predictive model for silicosis utilizing machine learning: a retrospective case-control study.

Frontiers in public health
OBJECTIVE: Due to the high global prevalence of silicosis and the ongoing challenges in its diagnosis, this pilot study aims to screen biomarkers from routine blood parameters and develop a multi-biomarker model for its early detection.

Hypothalamic atrophy in primary lateral sclerosis, assessed by convolutional neural network-based automatic segmentation.

Scientific reports
Primary lateral sclerosis (PLS) is a motor neuron disease (MND) which mainly affects upper motor neurons. Within the MND spectrum, PLS is much more slowly progressive than amyotrophic laterals sclerosis (ALS). `Classical` ALS is characterized by cata...

Combining machine learning and single-cell sequencing to identify key immune genes in sepsis.

Scientific reports
This research aimed to identify novel indicators for sepsis by analyzing RNA sequencing data from peripheral blood samples obtained from sepsis patients (n = 23) and healthy controls (n = 10). 5148 differentially expressed genes were identified using...

Anti-ceramide antibody and sphingosine-1-phosphate as potential biomarkers of unresectable non-small cell lung cancer.

Pathology oncology research : POR
OBJECTIVES: Spingosine-1-phosphate (S1P) and ceramides are bioactive sphingolipids that influence cancer cell fate. Anti-ceramide antibodies might inhibit the effects of ceramide. The aim of this study was to assess the potential role of circulating ...