European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
Apr 15, 2021
PURPOSE: AI algorithms have shown promise in medical image analysis. Previous studies of ASD clusters have analyzed alignment metrics-this study sought to complement these efforts by analyzing images of sagittal anatomical spinopelvic landmarks. We h...
International journal of molecular sciences
Apr 15, 2021
High-throughput analysis of biomass is necessary to ensure consistent and uniform feedstocks for agricultural and bioenergy applications and is needed to inform genomics and systems biology models. Pyrolysis followed by mass spectrometry such as mole...
Network-based methods for the analysis of drug-target interactions have gained attention and rely on the paradigm that a single drug can act on multiple targets rather than a single target. In this study, we have presented a novel approach to analyze...
IEEE/ACM transactions on computational biology and bioinformatics
Apr 8, 2021
A protein complex is a group of associated polypeptide chains which plays essential roles in the biological process. Given a graph representing protein-protein interactions (PPI) network, it is critical but non-trivial to detect protein complexes, th...
The question of molecular similarity is core in cheminformatics and is usually assessed via a comparison based on vectors of properties or molecular fingerprints. We recently exploited variational autoencoders to embed 6M molecules in a chemical spa...
International journal of molecular sciences
Mar 26, 2021
Molecular spectroscopy has been widely used to identify pesticides. The main limitation of this approach is the difficulty of identifying pesticides with similar molecular structures. When these pesticide residues are in trace and mixed states in pla...
Neural networks : the official journal of the International Neural Network Society
Mar 24, 2021
We introduce a novel adaptive version of the Neighborhood Retrieval Visualizer (NeRV). We maintain the advantages of the conventional NeRV method, while proposing an improvement of the data samples' neighborhood width calculation, in the input and ou...
Breast cancer is one of the leading causes of mortality in the world and it occurs in high frequency among women that carries away many lives. To detect cancer, extraction or segmentation of lesions/tumors is required. Segmentation process is very cr...
Cancer is a complex disease that deregulates cellular functions at various molecular levels (e.g., DNA, RNA, and proteins). Integrated multi-omics analysis of data from these levels is necessary to understand the aberrant cellular functions accountab...
Healthcare question answering (HQA) system plays a vital role in encouraging patients to inquire for professional consultation. However, there are some challenging factors in learning and representing the question corpus of HQA datasets, such as high...
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