BACKGROUND: Virtual patient (VP) simulations can be used to practice clinical reasoning (CR) in controlled learning environments. Traditional computer-based VP platforms often lack the authenticity and interactivity required for effective CR training...
Emerging evidence suggests that gut microbiota dysbiosis is associated with bone metabolism disorders, including osteopenia (ON) and osteoporosis (OP). However, multi-cohort integrated and association analyses remain underexplored. We conducted a com...
BACKGROUND: Mild cognitive impairment (MCI) represents a transitional stage to Alzheimer's disease (AD), making progression prediction crucial for timely intervention. Predictive models integrating clinical, laboratory, and survival data can enhance ...
BACKGROUND: Gout is the most common inflammatory arthritis. Recurrent flares are common among hospitalised patients and contribute to substantial clinical and economic burden. However, the accurate prediction of inpatient recurrence remains challengi...
BACKGROUND: Hypertension, one of the most common cardiovascular conditions worldwide, necessitates comprehensive management due to its association with multiple health risks. Effective control often involves lifestyle changes and continuous monitorin...
Depression, which is increasingly prevalent among older adults, has traditionally been diagnosed through symptom-based questionnaires. However, emerging evidence suggests that retinal changes could serve as objective biomarkers for depression. In thi...
BACKGROUND: Residual cardiovascular risk persists in patients with hypercholesterolemia despite lipid-lowering therapy, underscoring the importance of inflammation in ASCVD development. This study evaluated the relationship between Systemic Inflammat...
BACKGROUND AND OBJECTIVES: Epilepsy is a common neurologic disorder. Although antiseizure medications (ASMs) are the first-line treatment, identifying the most effective ASM for each individual remains a trial-and-error process. Genetic variation may...
BACKGROUND: Previous genomic efforts on chromosome 9p deletion and duplication syndromes have utilized low-resolution strategies (i.e., karyotypes, chromosome microarrays). These studies have provided important initial insights into these syndromes. ...
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