AIMC Topic: Cohort Studies

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Clinical characteristics and CKD care delivery in African American and American Indian or Alaska Native patients: A real-world cohort study.

BMC nephrology
BACKGROUND: Racially minoritized populations in the United States (US), notably African American (AA) and American Indian/Alaska Native (AI/AN), experience disproportionately higher rates of chronic kidney disease (CKD), diabetes, and hypertension co...

Application of image guided analyses to monitor fecal microbial composition and diversity in a human cohort.

Scientific reports
The critical role of gut microbiota in human health and disease has been increasingly illustrated over the past decades, with a significant amount of research demonstrating an unmet need for self-monitor of the fecal microbial composition in an easil...

Electrocardiographic sex index: a continuous representation of sex.

Biology of sex differences
Clinical risk calculators consider sex as a binary variable. However, sex is a complex trait with anatomic, physiologic, and metabolic attributes that are not easily summarized in this manner [1]. We propose a continuous representation of sex, the EC...

Mortality and antibiotic timing in deep learning-derived surviving sepsis campaign risk groups: a multicenter study.

Critical care (London, England)
BACKGROUND: The current Surviving Sepsis Campaign (SSC) guidelines provide recommendations on timing of administering antibiotics in sepsis patients based on probability of sepsis and presence of shock. However, there have been minimal efforts to str...

Characterizing individual and methodological risk factors for survey non-completion using machine learning: findings from the U.S. Millennium Cohort Study.

BMC medical research methodology
BACKGROUND: Missing survey data can threaten the validity and generalizability of findings from longitudinal cohort studies. Respondent characteristics and survey attributes may contribute to patterns of survey non-completion, a form of missing data ...

Integrated clinicopathological-radiomic-blood model for glioma survival prediction via machine learning: a multicenter cohort study.

Neurosurgical review
BACKGROUND: Glioma is characterized by a poor prognosis and limited possibilities for treatment. Previous studies have developed prediction models for glioma using genetic, clinical, pathological, imaging and other aspects; however, few studies have ...

Protocol for the REBOUND study: a cohort study to uncover fundamental mechanisms of accelerated ageing and impaired resilience following cancer surgery and treatment.

BMC geriatrics
BACKGROUND: Ageing is a heterogeneous process, which is associated with heterogeneous resilience in older people. Cancer surgery and treatment may be associated with accelerated ageing in some older people; studying this process will improve understa...

Machine learning-based prediction of celiac antibody seropositivity by biochemical test parameters.

Scientific reports
The diagnostic delay in celiac disease (CD) is currently a burden for individual and society. Biochemical tests may be used in risk-identification of CD to reduce the diagnostic delay, and we aimed to explore prediction models for CD antibody seropos...

Integrating CT radiomics and clinical features using machine learning to predict post-COVID pulmonary fibrosis.

Respiratory research
BACKGROUND: The lack of reliable biomarkers for the early detection and risk stratification of post-COVID-19 pulmonary fibrosis (PCPF) underscores the urgency advanced predictive tools. This study aimed to develop a machine learning-based predictive ...

Enhanced machine learning models for predicting three-year mortality in Non-STEMI patients aged 75 and above.

BMC geriatrics
BACKGROUND: Non-ST segment elevation myocardial infarction (Non-STEMI) is a severe cardiovascular condition mainly affecting individuals aged 75 and above, who are at higher risk of mortality due to age-related vulnerabilities and other health issues...