BACKGROUND: Racially minoritized populations in the United States (US), notably African American (AA) and American Indian/Alaska Native (AI/AN), experience disproportionately higher rates of chronic kidney disease (CKD), diabetes, and hypertension co...
The critical role of gut microbiota in human health and disease has been increasingly illustrated over the past decades, with a significant amount of research demonstrating an unmet need for self-monitor of the fecal microbial composition in an easil...
Clinical risk calculators consider sex as a binary variable. However, sex is a complex trait with anatomic, physiologic, and metabolic attributes that are not easily summarized in this manner [1]. We propose a continuous representation of sex, the EC...
BACKGROUND: The current Surviving Sepsis Campaign (SSC) guidelines provide recommendations on timing of administering antibiotics in sepsis patients based on probability of sepsis and presence of shock. However, there have been minimal efforts to str...
BACKGROUND: Missing survey data can threaten the validity and generalizability of findings from longitudinal cohort studies. Respondent characteristics and survey attributes may contribute to patterns of survey non-completion, a form of missing data ...
BACKGROUND: Glioma is characterized by a poor prognosis and limited possibilities for treatment. Previous studies have developed prediction models for glioma using genetic, clinical, pathological, imaging and other aspects; however, few studies have ...
BACKGROUND: Ageing is a heterogeneous process, which is associated with heterogeneous resilience in older people. Cancer surgery and treatment may be associated with accelerated ageing in some older people; studying this process will improve understa...
The diagnostic delay in celiac disease (CD) is currently a burden for individual and society. Biochemical tests may be used in risk-identification of CD to reduce the diagnostic delay, and we aimed to explore prediction models for CD antibody seropos...
BACKGROUND: The lack of reliable biomarkers for the early detection and risk stratification of post-COVID-19 pulmonary fibrosis (PCPF) underscores the urgency advanced predictive tools. This study aimed to develop a machine learning-based predictive ...
BACKGROUND: Non-ST segment elevation myocardial infarction (Non-STEMI) is a severe cardiovascular condition mainly affecting individuals aged 75 and above, who are at higher risk of mortality due to age-related vulnerabilities and other health issues...
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