AIMC Topic: Colorectal Neoplasms

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Robotic proctectomy for rectal cancer: analysis of 71 patients from a single institution.

The international journal of medical robotics + computer assisted surgery : MRCAS
BACKGROUND: Despite increasing use of robotic surgery for rectal cancer, few series have been published from the practice of generalizable US surgeons.

Gland Instance Segmentation Using Deep Multichannel Neural Networks.

IEEE transactions on bio-medical engineering
OBJECTIVE: A new image instance segmentation method is proposed to segment individual glands (instances) in colon histology images. This process is challenging since the glands not only need to be segmented from a complex background, they must also b...

Identification of miRNA-mRNA Modules in Colorectal Cancer Using Rough Hypercuboid Based Supervised Clustering.

Scientific reports
Differences in the expression profiles of miRNAs and mRNAs have been reported in colorectal cancer. Nevertheless, information on important miRNA-mRNA regulatory modules in colorectal cancer is still lacking. In this regard, this study presents an app...

Performance analysis of a machine learning flagging system used to identify a group of individuals at a high risk for colorectal cancer.

PloS one
Individuals with colorectal cancer (CRC) have a tendency to intestinal bleeding which may result in mild to severe iron deficiency anemia, but for many colon cancer patients hematological abnormalities are subtle. The fecal occult blood test (FOBT) i...

Correlating Quantitative Fecal Immunochemical Test Results with Neoplastic Findings on Colonoscopy in a Population-Based Colorectal Cancer Screening Program: A Prospective Study.

Canadian journal of gastroenterology & hepatology
. The Canadian Partnership Against Cancer (CPAC) recommends a fecal immunochemical test- (FIT-) positive predictive value (PPV) for all adenomas of ≥50%. We sought to assess FIT performance among average-risk participants of the British Columbia Colo...

Ileostomy creation in colorectal cancer surgery: risk of acute kidney injury and chronic kidney disease.

The Journal of surgical research
BACKGROUND: Ileostomy creation is associated with postoperative dehydration and readmission; however, the effect on renal function is unknown. Our goal was to characterize the impact of ileostomy creation on acute and chronic renal function.

DCAN: Deep contour-aware networks for object instance segmentation from histology images.

Medical image analysis
In histopathological image analysis, the morphology of histological structures, such as glands and nuclei, has been routinely adopted by pathologists to assess the malignancy degree of adenocarcinomas. Accurate detection and segmentation of these obj...

Machine Learning Meta-analysis of Large Metagenomic Datasets: Tools and Biological Insights.

PLoS computational biology
Shotgun metagenomic analysis of the human associated microbiome provides a rich set of microbial features for prediction and biomarker discovery in the context of human diseases and health conditions. However, the use of such high-resolution microbia...