AIMC Topic: Computational Biology

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TISNet-Enhanced Fully Convolutional Network with Encoder-Decoder Structure for Tongue Image Segmentation in Traditional Chinese Medicine.

Computational and mathematical methods in medicine
Extracting the tongue body accurately from a digital tongue image is a challenge for automated tongue diagnoses, as the blurred edge of the tongue body, interference of pathological details, and the huge difference in the size and shape of the tongue...

Integrating multi-omics data by learning modality invariant representations for improved prediction of overall survival of cancer.

Methods (San Diego, Calif.)
Breast and ovarian cancers are the second and the fifth leading causes of cancer death among women. Predicting the overall survival of breast and ovarian cancer patients can facilitate the therapeutics evaluation and treatment decision making. Multi-...

Machine learning-based classification and diagnosis of clinical cardiomyopathies.

Physiological genomics
Dilated cardiomyopathy (DCM) and ischemic cardiomyopathy (ICM) are two common types of cardiomyopathies leading to heart failure. Accurate diagnostic classification of different types of cardiomyopathies is critical for precision medicine in clinical...

A deep learning model to predict RNA-Seq expression of tumours from whole slide images.

Nature communications
Deep learning methods for digital pathology analysis are an effective way to address multiple clinical questions, from diagnosis to prediction of treatment outcomes. These methods have also been used to predict gene mutations from pathology images, b...

An Automatic Epilepsy Detection Method Based on Improved Inductive Transfer Learning.

Computational and mathematical methods in medicine
Epilepsy is a chronic disease caused by sudden abnormal discharge of brain neurons, causing transient brain dysfunction. The seizures of epilepsy have the characteristics of being sudden and repetitive, which has seriously endangered patients' health...

Predicting Gram-Positive Bacterial Protein Subcellular Location by Using Combined Features.

BioMed research international
There are a lot of bacteria in the environment, and Gram-positive bacteria are the most common ones. Some Gram-positive bacteria are very harmful to the human body, so it is significant to predict Gram-positive bacterial protein subcellular location....

Machine-learning approach expands the repertoire of anti-CRISPR protein families.

Nature communications
The CRISPR-Cas are adaptive bacterial and archaeal immunity systems that have been harnessed for the development of powerful genome editing and engineering tools. In the incessant host-parasite arms race, viruses evolved multiple anti-defense mechani...

Use Chou's 5-Step Rule to Predict DNA-Binding Proteins with Evolutionary Information.

BioMed research international
The knowledge of DNA-binding proteins would help to understand the functions of proteins better in cellular biological processes. Research on the prediction of DNA-binding proteins can promote the research of drug proteins and computer acidified drug...

Using an ontology of the human cardiovascular system to improve the classification of histological images.

Scientific reports
The advantages of automatically recognition of fundamental tissues using computer vision techniques are well known, but one of its main limitations is that sometimes it is not possible to classify correctly an image because the visual information is ...