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Computer Simulation

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Why implementing machine learning algorithms in the clinic is not a plug-and-play solution: a simulation study of a machine learning algorithm for acute leukaemia subtype diagnosis.

EBioMedicine
BACKGROUND: Artificial intelligence (AI) and machine learning (ML) algorithms have shown great promise in clinical medicine. Despite the increasing number of published algorithms, most remain unvalidated in real-world clinical settings. This study ai...

Performance of recurrent neural networks with Monte Carlo dropout for predicting pharmacokinetic parameters from dynamic contrast-enhanced magnetic resonance imaging data.

Journal of applied clinical medical physics
PURPOSE: To quantitatively evaluate the performance of two types of recurrent neural networks (RNNs), long short-term memory (LSTM) and gated recurrent units (GRU), using Monte Carlo dropout (MCD) to predict pharmacokinetic (PK) parameters from dynam...

Neural network-based dynamic target enclosing control for uncertain nonlinear multi-agent systems over signed networks.

Neural networks : the official journal of the International Neural Network Society
Neural networks have significant advantages in the estimation of uncertainty dynamics, which can afford highly accurate prediction outcomes and enhance control robustness. With this in mind, this study presents a neural network-based method to invest...

An in-depth examination of the fuzzy fractional cancer tumor model and its numerical solution by implicit finite difference method.

PloS one
The cancer tumor model serves a s a crucial instrument for understanding the behavior of different cancer tumors. Researchers have employed fractional differential equations to describe these models. In the context of time fractional cancer tumor mod...

Intrinsic plasticity coding improved spiking actor network for reinforcement learning.

Neural networks : the official journal of the International Neural Network Society
Deep reinforcement learning (DRL) exploits the powerful representational capabilities of deep neural networks (DNNs) and has achieved significant success. However, compared to DNNs, spiking neural networks (SNNs), which operate on binary signals, mor...

Accelerated quadratic penalty dynamic approaches with applications to distributed optimization.

Neural networks : the official journal of the International Neural Network Society
In this paper, we explore accelerated continuous-time dynamic approaches with a vanishing damping α/t, driven by a quadratic penalty function designed for linearly constrained convex optimization problems. We replace these linear constraints with pen...

Distributed nonconvex optimization subject to globally coupled constraints via collaborative neurodynamic optimization.

Neural networks : the official journal of the International Neural Network Society
In this paper, a recurrent neural network is proposed for distributed nonconvex optimization subject to globally coupled (in)equality constraints and local bound constraints. Two distributed optimization models, including a resource allocation proble...

Strategies for the design of biomimetic cell-penetrating peptides using AI-driven in silico tools for drug delivery.

Biomaterials advances
Cell-penetrating peptides (CPP) have gained rapid attention over the last 25 years; this is attributed to their versatility, customisation, and 'Trojan horse' delivery that evades the immune system. However, the current CPP rational design process is...

Passivity and robust passivity of inertial memristive neural networks with time-varying delays via non-reduced order method.

Neural networks : the official journal of the International Neural Network Society
This study examines the concepts of passivity and robust passivity in inertial memristive neural networks (IMNNs) that feature time-varying delays. By using non-smooth analysis and the passivity theorem, algebraic criteria for both passivity and robu...

Adaptive discrete-time neural prescribed performance control: A safe control approach.

Neural networks : the official journal of the International Neural Network Society
Most existing results on prescribed performance control (PPC), subject to input saturation and initial condition limitations, focus on continuous-time nonlinear systems. This article, as regards discrete-time nonlinear systems, is dedicated to constr...