AIMC Topic: Computer Simulation

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Cangrelor and AVN-944 as repurposable candidate drugs for hMPV: analysis entailed by AI-driven in silico approach.

Molecular diversity
Human metapneumovirus (hMPV) primarily causes respiratory tract infections in young children and older adults. According to the 2024 Human Pneumonia Etiology Research for Child Health (PERCH) study, hMPV is the second leading common cause of pneumoni...

Multi-objective optimization framework to plan laser ablation procedure for prostate tumors through a genetic algorithm.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVES: Prostate cancer is the most common form of cancer in the male population. While the survival rate is high, many patients undergo surgical procedures for prostate cancer that might never progress to clinical significance. As...

How Can Anomalous-Diffusion Neural Networks Under Connectomics Generate Optimized Spatiotemporal Dynamics.

IEEE transactions on neural networks and learning systems
Spatiotemporal dynamics in the brain have been recognized as strongly related to the formation of perceived and cognitive diseases, such as delusions and hallucinations in Alzheimer's disease. However, two practical considerations are rarely mentione...

Conditional Generative Models for Simulation of EMG During Naturalistic Movements.

IEEE transactions on neural networks and learning systems
Numerical models of electromyography (EMG) signals have provided a huge contribution to our fundamental understanding of human neurophysiology and remain a central pillar of motor neuroscience and the development of human-machine interfaces. However,...

Neural Network Circuits for Bionic Associative Memory and Temporal Order Memory Based on DNA Strand Displacement.

IEEE transactions on neural networks and learning systems
Pavlovian associative memory plays an important role in our daily life and work. The realization of Pavlovian associative memory at the deoxyribonucleic acid (DNA) molecular level will promote the development of biological computing and broaden the a...

On the Computational Complexity of Spiking Neural Membrane Systems with Colored Spikes.

International journal of neural systems
Spiking Neural P Systems are parallel and distributed computational models inspired by biological neurons, emerging from membrane computing and applied to solving computationally difficult problems. This paper focuses on the computational complexity ...

Artificial-intelligence-driven Innovations in Mechanistic Computational Modeling and Digital Twins for Biomedical Applications.

Journal of molecular biology
Understanding of complex biological systems remains a significant challenge due to their high dimensionality, nonlinearity, and context-specific behavior. Artificial intelligence (AI) and mechanistic modeling are becoming essential tools for studying...

RNN-Based Full Waveform Inversion for Robust Multi-Parameter Bone Quantitative Imaging.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: The full waveform inversion (FWI) method plays a significant role in bone quantitative imaging. It is shown that even a small deviation in transducer positions can lead to a considerable variation in frequency-domain signals...

Statistical algorithms for the analysis of deleterious genetic mutations.

Bio Systems
We present algorithms for model selection and parameter estimation concerning deleterious genetic mutations. Three models are considered: single gene mutation, double cross-effect mutations or no genetic cause. Each of these models include unknown pa...

Swimming in the "Matrix": VR fish pass the Turing test using a simple control law for collective behavior.

Science robotics
Immersive virtual reality reveals that a simple control model from fish schooling can be used to control autonomous vehicles.