AIMC Topic: Computer Simulation

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Deep learning-assisted identification and localization of ductal carcinoma from bulk tissue in-silico models generated through polarized Monte Carlo simulations.

Biomedical physics & engineering express
Despite significant progress in diagnosis and treatment, breast cancer remains a formidable health challenge, emphasizing the continuous need for research. This simulation study uses polarized Monte Carlo approach to identify and locate breast cancer...

Loss formulations for assumption-free neural inference of SDE coefficient functions.

NPJ systems biology and applications
Stochastic differential equations (SDEs) are one of the most commonly studied probabilistic dynamical systems, and widely used to model complex biological processes. Building upon the previously introduced idea of performing inference of dynamical sy...

Adaptive Synaptic Scaling in Spiking Networks for Continual Learning and Enhanced Robustness.

IEEE transactions on neural networks and learning systems
Synaptic plasticity plays a critical role in the expression power of brain neural networks. Among diverse plasticity rules, synaptic scaling presents indispensable effects on homeostasis maintenance and synaptic strength regulation. In the current mo...

A Generative Shape Compositional Framework to Synthesize Populations of Virtual Chimeras.

IEEE transactions on neural networks and learning systems
Generating virtual organ populations that capture sufficient variability while remaining plausible is essential to conduct in silico trials (ISTs) of medical devices. However, not all anatomical shapes of interest are always available for each indivi...

Estimation of Ganciclovir Exposure in Adults Transplant Patients by Machine Learning.

The AAPS journal
INTRODUCTION: Valganciclovir, a prodrug of ganciclovir (GCV), is used to prevent cytomegalovirus infection after transplantation, with doses adjusted based on creatinine clearance (CrCL) to target GCV AUC0-24 h of 40-60 mg*h/L. This sometimes leads t...

Design and implementation of an independent-drive bionic dragonfly robot.

Bioinspiration & biomimetics
Bionic flapping wing robots achieve flight by imitating animal flapping wings, which are safe, flexible, and efficient. Their practicality and human-machine symbiosis in narrow and complex environments are better than traditional fixed-wing or multir...

AI/ML modeling to enhance the capability of in vitro and in vivo tests in predicting human carcinogenicity.

Mutation research. Genetic toxicology and environmental mutagenesis
This study aimed to develop an in silico model for predicting human carcinogenicity using advanced deep learning techniques, specifically Graph Neural Networks (GNN), through a multitask learning (MTL) approach. The MTL framework leveraged auxiliary ...

A springtail-inspired multimodal walking-jumping microrobot.

Science robotics
Although legged robots have demonstrated effective mobility in some natural settings, as robot size decreases, obstacles in their environment become challenging to overcome. Small arthropods scale obstacles many times their size through jumps powered...

Adaptive control and state error prediction of flexible manipulators using radial basis function neural network and dynamic surface control method.

PloS one
This paper introduces a novel control strategy for managing the uncertainties in flexible joint manipulators, incorporating a Radial Basis Function Neural Network (RBFNN) with Adaptive Dynamic Surface Control (ADSC). This strategy innovatively utiliz...