PURPOSE OF REVIEW: Predicting treatment response and optimizing treatment regimen in patients with neovascular age-related macular degeneration (nAMD) remains challenging. Artificial intelligence-based tools have the potential to increase confidence ...
PURPOSE OF REVIEW: In this article, we introduce the concept of model interpretability, review its applications in deep learning models for clinical ophthalmology, and discuss its role in the integration of artificial intelligence in healthcare.
DNA-bound proteins are essential elements for the maintenance, regulation, and use of the genome. The time they spend bound to DNA provides useful information on their stability within protein complexes and insight into the understanding of biologica...
Associative memories enjoy many interesting properties in terms of error correction capabilities, robustness to noise, storage capacity, and retrieval performance, and their usage spans over a large set of applications. In this letter, we investigate...
Catheters used for endovascular navigation in interventional procedures lack dexterity at the distal tip. Neurointerventionists, in particular, encounter challenges in up to 25% of aneurysm cases largely due to the inability to steer and navigate the...
Mathematical biosciences and engineering : MBE
Aug 3, 2021
For the existing Closed Set Recognition (CSR) methods mistakenly identify unknown jamming signals as a known class, a Conditional Gaussian Encoder (CG-Encoder) for 1-dimensional signal Open Set Recognition (OSR) is designed. The network retains the o...
Proceedings of the National Academy of Sciences of the United States of America
Aug 3, 2021
Single-particle tracking (SPT) is a key tool for quantitative analysis of dynamic biological processes and has provided unprecedented insights into a wide range of systems such as receptor localization, enzyme propulsion, bacteria motility, and drug ...
Journal of nanoscience and nanotechnology
Aug 1, 2021
Synaptic devices, which are considered as one of the most important components of neuromorphic system, require a memory effect to store weight values, a high integrity for compact system, and a wide window to guarantee an accurate programming between...
Journal of the American Medical Informatics Association : JAMIA
Jul 30, 2021
OBJECTIVE: We introduce Medical evidence Dependency (MD)-informed attention, a novel neuro-symbolic model for understanding free-text clinical trial publications with generalizability and interpretability.
Accurate and individualized prediction of response to therapies is central to precision medicine. However, because of the generally complex and multifaceted nature of clinical drug response, realizing this vision is highly challenging, requiring inte...
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