BACKGROUND: Post-COVID conditions (PCC) are difficult to characterize, diagnose, predict, and treat due to overlapping symptoms and poorly understood pathology. Identifying inflammatory profiles may improve clinical prognostication and trial endpoint...
BACKGROUND: Transformer-based neural networks excel in modelling high-dimensional, time-series data with complex dependencies. This proof-of-concept study applies a transformer-X-learner framework to estimate treatment effects using real-world data, ...
Journal of chemical information and modeling
Jul 14, 2025
A critical assessment of computational hit-finding experiments (CACHE) challenge was conducted to predict ligands for the SARS-CoV-2 Nsp13 helicase RNA binding site, a highly conserved COVID-19 target. Twenty-three participating teams comprised of co...
European journal of medicinal chemistry
Jul 5, 2025
Bioactivity optimization is a crucial and technical task in the early stages of drug discovery, traditionally carried out through iterative substituent optimization, a process that is often both time-consuming and expensive. To address this challenge...
Point-of-Care Testing (POCT) is rapidly increasing, providing quick, user-friendly, and portable diagnostic tools. Lateral flow assays (LFAs) have been central to POCT, administering fast and cost-effective diagnosis. However, traditional LFAs are li...
Discrete wavelet transforms have been applied in many machine learning models for the analysis of COVID-19; however, little is known about the impact of combined multilevel wavelet decompositions for the disease identification. This study proposes a ...
A machine learning integrated SERS sensing platform is developed for a single-shot, receptor-free, rapid detection and classification of five respiratory viruses including Influenza A, Respiratory Syncytial Virus (RSV), Human Rhinoviruses (Rhino), an...
Recurrent waves of viral infection necessitate vaccines and therapeutics that remain effective against emerging viruses. Our ability to evaluate interventions is currently limited to assessments against past or circulating variants, which likely diff...
Journal of health organization and management
Jun 5, 2025
PURPOSE: Digital health or digital healthcare, is a broad, multidisciplinary concept that includes concepts from an intersection between technology and healthcare. Digital health applies digital transformation to the healthcare field, incorporating s...
Adeno-associated virus (AAV) is a non-enveloped DNA virus infecting a wide variety of species, tissues, and cell types, which is recognized as a safe and effective method for delivering therapeutic transgenes. AAV vector is the most popular viral gen...
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