INTRODUCTION: Valganciclovir, a prodrug of ganciclovir (GCV), is used to prevent cytomegalovirus infection after transplantation, with doses adjusted based on creatinine clearance (CrCL) to target GCV AUC0-24 h of 40-60 mg*h/L. This sometimes leads t...
Radiocontrast media is a major cause of nephrotoxic acute kidney injury(AKI). Contrast-enhanced CT(CE-CT) is commonly performed in emergency departments(ED). Predicting individualized risks of contrast-associated AKI(CA-AKI) in ED patients is challen...
Traditional methods for diagnosing chronic kidney disease (CKD) via laboratory data may not be capable of identifying early kidney disease. Kidney biopsy is unsuitable for regular screening, and imaging tests are costly and time-consuming. Several st...
Chronic kidney disease (CKD) is a global health concern with early detection playing a pivotal role in effective management. Machine learning models demonstrate promise in CKD detection, yet the impact on detection and classification using different ...
International journal of medical informatics
Feb 4, 2025
Increased monitoring of health-related data for ICU patients holds great potential for the early prediction of medical outcomes. Research on whether the use of clinical notes and concepts from knowledge bases can improve the performance of prediction...
BACKGROUND: Creatinine-based estimated glomerular filtration rate (eGFR) equations are widely used in clinical practice but exhibit inherent limitations. On the other side, measuring GFR is time consuming and not available in routine clinical practic...
BACKGROUND: Acute kidney injury (AKI) and acute kidney disease (AKD) are prevalent among pediatric patients, both linked to increased mortality and extended hospital stays. Early detection of kidney injury is crucial for improving outcomes. This stud...
Fluid overload is associated with increased morbidity and mortality after pediatric cardiac surgery. Management of fluid overload can be difficult and conventional tools may increase the risk of acute kidney injury. This study aimed to study the effe...
BACKGROUND: Plasma cell dyscrasias encompass a diverse set of disorders, where early and precise diagnosis is essential for optimizing patient outcomes. Despite advancements, current diagnostic methodologies remain underutilized in applying artificia...
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Nov 3, 2024
Metabolites serve as vital biomarkers, reflecting physiological and pathological states and offering insights into disease progression and early detection. This study introduces an advanced analytical technique integrating label-free Surface-Enhanced...
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