AIMC Topic: Data Mining

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Extracting drug-enzyme relation from literature as evidence for drug drug interaction.

Journal of biomedical semantics
BACKGROUND: Information about drug-drug interactions (DDIs) is crucial for computational applications such as pharmacovigilance and drug repurposing. However, existing sources of DDIs have the problems of low coverage, low accuracy and low agreement....

Bio-SCoRes: A Smorgasbord Architecture for Coreference Resolution in Biomedical Text.

PloS one
Coreference resolution is one of the fundamental and challenging tasks in natural language processing. Resolving coreference successfully can have a significant positive effect on downstream natural language processing tasks, such as information extr...

A categorical analysis of coreference resolution errors in biomedical texts.

Journal of biomedical informatics
BACKGROUND: Coreference resolution is an essential task in information extraction from the published biomedical literature. It supports the discovery of complex information by linking referring expressions such as pronouns and appositives to their re...

Speculation detection for Chinese clinical notes: Impacts of word segmentation and embedding models.

Journal of biomedical informatics
Speculations represent uncertainty toward certain facts. In clinical texts, identifying speculations is a critical step of natural language processing (NLP). While it is a nontrivial task in many languages, detecting speculations in Chinese clinical ...

Natural Language Processing for Cohort Discovery in a Discharge Prediction Model for the Neonatal ICU.

Applied clinical informatics
OBJECTIVES: Discharging patients from the Neonatal Intensive Care Unit (NICU) can be delayed for non-medical reasons including the procurement of home medical equipment, parental education, and the need for children's services. We previously created ...

Temporal data representation, normalization, extraction, and reasoning: A review from clinical domain.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: We live our lives by the calendar and the clock, but time is also an abstraction, even an illusion. The sense of time can be both domain-specific and complex, and is often left implicit, requiring significant domain knowledg...

Extending (Q)SARs to incorporate proprietary knowledge for regulatory purposes: A case study using aromatic amine mutagenicity.

Regulatory toxicology and pharmacology : RTP
Statistical-based and expert rule-based models built using public domain mutagenicity knowledge and data are routinely used for computational (Q)SAR assessments of pharmaceutical impurities in line with the approach recommended in the ICH M7 guidelin...

Data mining framework for identification of myocardial infarction stages in ultrasound: A hybrid feature extraction paradigm (PART 2).

Computers in biology and medicine
Early expansion of infarcted zone after Acute Myocardial Infarction (AMI) has serious short and long-term consequences and contributes to increased mortality. Thus, identification of moderate and severe phases of AMI before leading to other catastrop...

Fusing Data Mining, Machine Learning and Traditional Statistics to Detect Biomarkers Associated with Depression.

PloS one
BACKGROUND: Atheoretical large-scale data mining techniques using machine learning algorithms have promise in the analysis of large epidemiological datasets. This study illustrates the use of a hybrid methodology for variable selection that took acco...

Adapting content-based image retrieval techniques for the semantic annotation of medical images.

Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
The automatic annotation of medical images is a prerequisite for building comprehensive semantic archives that can be used to enhance evidence-based diagnosis, physician education, and biomedical research. Annotation also has important applications i...