AIMC Topic: Databases, Factual

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Towards the automated economic assessment of newborn screening for rare diseases.

Journal of biomedical informatics
OBJECTIVE: Economic assessments of newborn screening programs for rare diseases involve the use of models and require huge efforts to synthesize information from different sources. Sharing and automatically or semi-automatically reusing this informat...

Deep Learning to Therapeutically Target Unreported Complexes.

Trends in pharmacological sciences
The disruption of large protein-protein (PP) interfaces remains a challenge in targeted therapy. Designing drugs that compete with binding partners is daunting, especially when the structure of the protein complex is unknown. To address the problem w...

Reconstructing faces from fMRI patterns using deep generative neural networks.

Communications biology
Although distinct categories are reliably decoded from fMRI brain responses, it has proved more difficult to distinguish visually similar inputs, such as different faces. Here, we apply a recently developed deep learning system to reconstruct face im...

Recomputation of the Dense Layers for Performance Improvement of DCNN.

IEEE transactions on pattern analysis and machine intelligence
Gradient descent optimization of learning has become a paradigm for training deep convolutional neural networks (DCNN). However, utilizing other learning strategies in the training process of the DCNN has rarely been explored by the deep learning (DL...

Evaluating and Enhancing the Generalization Performance of Machine Learning Models for Physical Activity Intensity Prediction From Raw Acceleration Data.

IEEE journal of biomedical and health informatics
PURPOSE: To evaluate and enhance the generalization performance of machine learning physical activity intensity prediction models developed with raw acceleration data on populations monitored by different activity monitors.

End-to-end lung cancer screening with three-dimensional deep learning on low-dose chest computed tomography.

Nature medicine
With an estimated 160,000 deaths in 2018, lung cancer is the most common cause of cancer death in the United States. Lung cancer screening using low-dose computed tomography has been shown to reduce mortality by 20-43% and is now included in US scree...

Mixed convolutional and long short-term memory network for the detection of lethal ventricular arrhythmia.

PloS one
Early defibrillation by an automated external defibrillator (AED) is key for the survival of out-of-hospital cardiac arrest (OHCA) patients. ECG feature extraction and machine learning have been successfully used to detect ventricular fibrillation (V...

Machine learning prediction of nanoparticle in vitro toxicity: A comparative study of classifiers and ensemble-classifiers using the Copeland Index.

Toxicology letters
Nano-Particles (NPs) are well established as important components across a broad range of products from cosmetics to electronics. Their utilization is increasing with their significant economic and societal potential yet to be fully realized. Inroads...

Digital hair segmentation using hybrid convolutional and recurrent neural networks architecture.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: Skin melanoma is one of the major health problems in many countries. Dermatologists usually diagnose melanoma by visual inspection of moles. Digital hair removal can provide a non-invasive way to remove hair and hair-like re...

A machine learning-based approach for predicting the outbreak of cardiovascular diseases in patients on dialysis.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: Patients with End- Stage Kidney Disease (ESKD) have a unique cardiovascular risk. This study aims at predicting, with a certain precision, death and cardiovascular diseases in dialysis patients.