Genetic variants can affect protein function by driving aberrant subcellular localization. However, comprehensive analysis of how mutations promote tumor progression by influencing nuclear localization is currently lacking. Here, we systematically ch...
Precision medicine requires accurate identification of clinically relevant patient subgroups. Electronic health records provide major opportunities for leveraging machine learning approaches to uncover novel patient subgroups. However, many existing ...
American journal of Alzheimer's disease and other dementias
Mar 14, 2025
White matter hyperintensity (WMH) is associated with cognitive impairment. In this study, 79 patients with WMH from hospital 1 were randomly divided into a training set (62 patients) and an internal validation set (17 patients). In addition, 29 WMH p...
BACKGROUND: Patients with chronic kidney disease (CKD) are considered the primary population at risk for post-contrast acute kidney injury (PC-AKI), yet there are few predictive tools specifically designed for this vulnerable population.
Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
Mar 13, 2025
Accurate segmentation of the tumor regions of nasopharyngeal carcinoma (NPC) is of significant importance for radiotherapy of NPC. However, the precision of existing automatic segmentation methods for NPC remains inadequate, primarily manifested in t...
Schizophrenia (SZ) is a complex mental disorder characterized by a profound disruption in cognition and emotion, often resulting in a distorted perception of reality. Magnetic resonance imaging (MRI) is an essential tool for diagnosing SZ which helps...
OBJECTIVE: To evaluate whether deep learning (DL) analysis of intratumor subregion based on dynamic contrast-enhanced MRI (DCE-MRI) can help predict Ki-67 expression level in breast cancer.
To date, the effect of cryopreservation on microcracks in the dental enamel remains unclear. These enamel microcracks are very thin, at the limit of visibility and their segmentation is beyond the capabilities of traditional image analysis. The objec...
Pancreatic cancer is a lethal invasive tumor with one of the worst prognosis. Accurate and reliable segmentation for pancreas and pancreatic cancer on computerized tomography (CT) images is vital in clinical diagnosis and treatment. Although certain ...
The understanding of the convoluted evolution of infant brain networks during the first postnatal year is pivotal for identifying the dynamics of early brain connectivity development. Thanks to the valuable insights into the brain's anatomy, existing...
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