AIMC Topic: Deep Learning

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Automated confidence estimation in deep learning auto-segmentation for brain organs at risk on MRI for radiotherapy.

Journal of applied clinical medical physics
PURPOSE: We have built a novel AI-driven QA method called AutoConfidence (ACo), to estimate segmentation confidence on a per-voxel basis without gold standard segmentations, enabling robust, efficient review of automated segmentation (AS). We have de...

Interpreting cis-regulatory interactions from large-scale deep neural networks.

Nature genetics
The rise of large-scale, sequence-based deep neural networks (DNNs) for predicting gene expression has introduced challenges in their evaluation and interpretation. Current evaluations align DNN predictions with orthogonal experimental data, providin...

TAG-SPARK: Empowering High-Speed Volumetric Imaging With Deep Learning and Spatial Redundancy.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Two-photon high-speed fluorescence calcium imaging stands as a mainstream technique in neuroscience for capturing neural activities with high spatiotemporal resolution. However, challenges arise from the inherent tradeoff between acquisition speed an...

A Nanoparticle-Based Artificial Ear for Personalized Classification of Emotions in the Human Voice Using Deep Learning.

ACS applied materials & interfaces
Artificial intelligence and human-computer interaction advances demand bioinspired sensing modalities capable of comprehending human affective states and speech. However, endowing skin-like interfaces with such intricate perception abilities remains ...

Predicting Biochemical and Physiological Parameters: Deep Learning from IgG Glycome Composition.

International journal of molecular sciences
In immunoglobulin G (IgG), -glycosylation plays a pivotal role in structure and function. It is often altered in different diseases, suggesting that it could be a promising health biomarker. Studies indicate that IgG glycosylation not only associates...

Splam: a deep-learning-based splice site predictor that improves spliced alignments.

Genome biology
The process of splicing messenger RNA to remove introns plays a central role in creating genes and gene variants. We describe Splam, a novel method for predicting splice junctions in DNA using deep residual convolutional neural networks. Unlike previ...

Application research on the diagnosis of classic trigeminal neuralgia based on VB-Net technology and radiomics.

BMC medical imaging
BACKGROUND: This study aims to utilize the deep learning method of VB-Net to locate and segment the trigeminal nerve, and employ radiomics methods to distinguish between CTN patients and healthy individuals.

Accuracy of deep learning in the differential diagnosis of coronary artery stenosis: a systematic review and meta-analysis.

BMC medical imaging
BACKGROUND: In recent years, as deep learning has received widespread attention in the field of heart disease, some studies have explored the potential of deep learning based on coronary angiography (CAG) or coronary CT angiography (CCTA) images in d...

Deep neural network models for cell type prediction based on single-cell Hi-C data.

BMC genomics
BACKGROUND: Cell type prediction is crucial to cell type identification of genomics, cancer diagnosis and drug development, and it can solve the time-consuming and difficult problem of cell classification in biological experiments. Therefore, a compu...

Leveraging immuno-fluorescence data to reduce pathologist annotation requirements in lung tumor segmentation using deep learning.

Scientific reports
The main bottleneck in training a robust tumor segmentation algorithm for non-small cell lung cancer (NSCLC) on H&E is generating sufficient ground truth annotations. Various approaches for generating tumor labels to train a tumor segmentation model ...