AIMC Topic: Depressive Disorder, Major

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Relative importance of symptoms, cognition, and other multilevel variables for psychiatric disease classifications by machine learning.

Psychiatry research
This study used machine-learning algorithms to make unbiased estimates of the relative importance of various multilevel data for classifying cases with schizophrenia (n = 60), schizoaffective disorder (n = 19), bipolar disorder (n = 20), unipolar dep...

Evaluating the evidence for biotypes of depression: Methodological replication and extension of.

NeuroImage. Clinical
BACKGROUND: Psychiatric disorders are highly heterogeneous, defined based on symptoms with little connection to potential underlying biological mechanisms. A possible approach to dissect biological heterogeneity is to look for biologically meaningful...

Classifying major depression patients and healthy controls using EEG, eye tracking and galvanic skin response data.

Journal of affective disorders
OBJECTIVE: Major depression disorder (MDD) is one of the most prevalent mental disorders worldwide. Diagnosing depression in the early stage is crucial to treatment process. However, due to depression's comorbid nature and the subjectivity in diagnos...

Artificial intelligence based discovery of the association between depression and chronic fatigue syndrome.

Journal of affective disorders
BACKGROUND: Both of the modern medicine and the traditional Chinese medicine classify depressive disorder (DD) and chronic fatigue syndrome (CFS) to one type of disease. Unveiling the association between depressive and the fatigue diseases provides a...

Low-rank network signatures in the triple network separate schizophrenia and major depressive disorder.

NeuroImage. Clinical
Brain imaging studies have revealed that functional and structural brain connectivity in the so-called triple network (i.e., default mode network (DMN), salience network (SN) and central executive network (CEN)) are consistently altered in schizophre...

Electroconvulsive Therapy Induces Cortical Morphological Alterations in Major Depressive Disorder Revealed with Surface-Based Morphometry Analysis.

International journal of neural systems
Although electroconvulsive therapy (ECT) is one of the most effective treatments for major depressive disorder (MDD), the mechanism underlying the therapeutic efficacy and side effects of ECT remains poorly understood. Here, we investigated alteratio...

Using neuroimaging to predict relapse in stimulant dependence: A comparison of linear and machine learning models.

NeuroImage. Clinical
OBJECTIVE: Relapse rates are consistently high for stimulant user disorders. In order to obtain prognostic information about individuals in treatment, machine learning models have been applied to neuroimaging and clinical data. Yet few efforts have b...

Predicting the naturalistic course of depression from a wide range of clinical, psychological, and biological data: a machine learning approach.

Translational psychiatry
Many variables have been linked to different course trajectories of depression. These findings, however, are based on group comparisons with unknown translational value. This study evaluated the prognostic value of a wide range of clinical, psycholog...

Machine learning in major depression: From classification to treatment outcome prediction.

CNS neuroscience & therapeutics
AIMS: Major depression disorder (MDD) is the single greatest cause of disability and morbidity, and affects about 10% of the population worldwide. Currently, there are no clinically useful diagnostic biomarkers that are able to confirm a diagnosis of...