AIMC Topic: Diabetes Mellitus, Type 2

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Identification and validation of the diagnostic biomarker MFAP5 for CAVD with type 2 diabetes by bioinformatics analysis.

Frontiers in immunology Dec 19, 2024
INTRODUCTION: Calcific aortic valve disease (CAVD) is increasingly prevalent among the aging population, and there is a notable lack of drug therapies. Consequently, identifying novel drug targets will be of utmost importance. Given that type 2 diabe...
Computational Biology Transcriptome Databases, Genetic Calcinosis Diabetes Mellitus, Type 2 Humans Aortic Valve Stenosis Protein Interaction Maps Machine Learning Gene Regulatory Networks Biomarkers Gene Expression Profiling Aortic Valve
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Potential shared mechanisms in atopic dermatitis and type 2 diabetes identified via transcriptomic and machine learning approaches.

Scientific reports Dec 16, 2024
Although atopic dermatitis (AD) and type 2 diabetes mellitus (T2DM) may appear clinically and pathophysiologically unrelated, AD is a common skin disease characterized by chronic inflammation and skin barrier dysfunction, whereas T2DM is a metabolic ...
Diabetes Mellitus, Type 2 Dermatitis, Atopic Receptors, CCR1 Humans Machine Learning Biomarkers Gene Expression Profiling Transcriptome
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Early Detection of Dementia in Populations With Type 2 Diabetes: Predictive Analytics Using Machine Learning Approach.

Journal of medical Internet research Dec 11, 2024
BACKGROUND: The possible association between diabetes mellitus and dementia has raised concerns, given the observed coincidental occurrences.
Neural Networks, Computer Machine Learning Retrospective Studies Female Humans Dementia Diabetes Mellitus, Type 2 Hypoglycemic Agents Aged Taiwan Aged, 80 and over Early Diagnosis Male Middle Aged
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Modeling the fasting blood glucose response to basal insulin adjustment in type 2 diabetes: An explainable machine learning approach on real-world data.

International journal of medical informatics Dec 9, 2024
INTRODUCTION: Optimal basal insulin titration for people with type 2 diabetes is vital to effectively reducing the risk of complications. However, a sizeable proportion of people (30-50 %) remain in suboptimal glycemic control six months post-initiat...
Insulin Diabetes Mellitus, Type 2 Male Hypoglycemic Agents Humans Middle Aged Machine Learning Fasting Female Blood Glucose Aged
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Machine learning approaches and genetic determinants that influence the development of type 2 diabetes mellitus: a genetic association study in Brazilian patients.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas Dec 2, 2024
This genetic association study including 120 patients with type 2 diabetes mellitus (T2DM) and 166 non-diabetic individuals aimed to investigate the association of polymorphisms in the genes GSTM1 and GSTT1 (gene deletion), GSTP1 (rs1695), ACE (rs464...
Middle Aged Humans Brazil Machine Learning Case-Control Studies Vascular Endothelial Growth Factor A Risk Factors Genetic Predisposition to Disease Female Polymorphism, Genetic Diabetes Mellitus, Type 2 Glutathione Transferase Polymorphism, Single Nucleotide Aged Glutathione S-Transferase pi Genotype Adult Genetic Association Studies Male
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Interpretable time-series neural turing machine for prognostic prediction of patients with type 2 diabetes in physician-pharmacist collaborative clinics.

International journal of medical informatics Nov 29, 2024
BACKGROUND: Type 2 diabetes (T2D) has become a serious health threat globally. However, the existing approaches for diabetes prediction mainly had difficulty in addressing multiple time-series features. This study aims to provide an adjunctive tool f...
Male Middle Aged Diabetes Mellitus, Type 2 Humans Prognosis Female Aged Neural Networks, Computer Physicians
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Machine learning algorithms mimicking specialists decision making on initial treatment for people with type 2 diabetes mellitus in Japan diabetes data management study (JDDM76).

Diabetes & metabolic syndrome Nov 29, 2024
OBJECTIVE: To evaluate whether typical machine learning models that mimic specialists' care can successfully reproduce information, not only on whether to prescribe medications but also which hypoglycemic agents to prescribe as initial treatment for ...
Humans Machine Learning Algorithms Decision Making Japan Prognosis Middle Aged Specialization Female Diabetes Mellitus, Type 2 Aged Hypoglycemic Agents Male Follow-Up Studies
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A machine learning model for predicting worsening renal function using one-year time series data in patients with type 2 diabetes.

Journal of diabetes investigation Nov 13, 2024
BACKGROUND AND AIMS: To prevent end-stage renal disease caused by diabetic kidney disease, we created a predictive model for high-risk patients using machine learning.
Male Middle Aged Disease Progression Diabetes Mellitus, Type 2 Diabetic Nephropathies Kidney Glomerular Filtration Rate Machine Learning Prognosis Female Aged Humans
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Enhancing type 2 diabetes mellitus prediction by integrating metabolomics and tree-based boosting approaches.

Frontiers in endocrinology Nov 11, 2024
BACKGROUND: Type 2 diabetes mellitus (T2DM) is a global health problem characterized by insulin resistance and hyperglycemia. Early detection and accurate prediction of T2DM is crucial for effective management and prevention. This study explores the ...
Male Middle Aged Case-Control Studies Diabetes Mellitus, Type 2 Metabolomics Humans Prognosis Artificial Intelligence Female Machine Learning Aged Algorithms Adult Biomarkers
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Screening of CAD-related secretory genes associated with type II diabetes based on comprehensive bioinformatics analysis and machine learning.

BMC cardiovascular disorders Nov 5, 2024
BACKGROUND: Type II diabetes mellitus (T2DM) is strongly linked with a heightened risk of coronary artery disease (CAD). Exploring biological targets common to T2DM and CAD is essential for CAD intervention strategies.
Middle Aged Gene Expression Profiling Transcriptome Diabetes Mellitus, Type 2 Machine Learning Female Aged Male Databases, Genetic Coronary Artery Disease Myocytes, Cardiac Myocytes, Smooth Muscle Fibroblast Growth Factor 7 Single-Cell Analysis Gene Regulatory Networks Genetic Predisposition to Disease Computational Biology Humans
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