AIMC Topic: Diabetic Nephropathies

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Multi-modal models using fMRI, urine and serum biomarkers for classification and risk prognosis in diabetic kidney disease.

Diabetes, obesity & metabolism
BACKGROUND: Functional magnetic resonance imaging (fMRI) is a powerful tool for non-invasive evaluation of micro-changes in the kidneys. This study aims to develop classification and prognostic models based on multi-modal data.

Identification of hub genes involved in the pathogenesis of diabetic nephropathy: A multi-omics study integrating machine learning, mendelian randomization and mediation analysis.

Diabetes, obesity & metabolism
BACKGROUND: Diabetic nephropathy (DN), affecting 30%-40% of diabetic patients, is the leading cause of end-stage renal disease worldwide. This study aims to identify diagnostic biomarkers and explore potential gene-metabolite interactions in DN patho...

The impact of clinical history on the predictive performance of machine learning and deep learning models for renal complications of diabetes.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: Diabetes is a chronic disease characterised by a high risk of developing diabetic nephropathy. The early identification of individuals at heightened risk of such complications or their exacerbation can be crucial to set a co...

Integrating bioinformatics and machine learning to identify glomerular injury genes and predict drug targets in diabetic nephropathy.

Scientific reports
Diabetes mellitus (DM) is a chronic metabolic disorder that poses significant challenges to public health. Among its various complications, diabetic nephropathy (DN) emerges as a critical microvascular complication associated with high mortality rate...

Deep learning algorithms to detect diabetic kidney disease from retinal photographs in multiethnic populations with diabetes.

Journal of the American Medical Informatics Association : JAMIA
OBJECTIVE: To develop a deep learning algorithm (DLA) to detect diabetic kideny disease (DKD) from retinal photographs of patients with diabetes, and evaluate performance in multiethnic populations.

Pattern and predictors of urine protein excretion among patients with type 2 diabetes attending a single tertiary hospital in Lagos, Nigeria.

Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia
Testing for proteinuria is used to screen for diabetic nephropathy. However, significant proportion of diabetics has normal urine protein excretion despite impaired renal function. We aimed to determine the factors predicting increased urine protein ...