AIMC Topic: Disease Progression
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Multilevel Hydrangea-like Heterogeneous Oxides Enabling COVID-19 Progression Surveillance via Metabolic Fingerprints.
Analytical chemistry
Jul 23, 2025
Coronavirus disease 2019 (COVID-19), a global pandemic infectious disease, requires early diagnosis and dynamic monitoring to enable timely intervention and reduce the risks of adverse outcomes. To support these needs, we developed an advanced metabo...
Collaborative assessment of the risk of postoperative progression in early-stage non-small cell lung cancer: a robust federated learning model.
Cancer imaging : the official publication of the International Cancer Imaging Society
Jul 18, 2025
BACKGROUND: While the TNM staging system provides valuable insights into the extent of disease, predicting postoperative progression in early-stage non-small cell lung cancer (NSCLC) remains a significant challenge. An effective bioimaging prognostic...
Image-based inference of tumor cell trajectories enables large-scale cancer progression analysis.
Science advances
Jul 18, 2025
Current approaches to estimating cell trajectories, tumor progression dynamics, and cell population diversity of tumor microenvironment often depend on single-cell RNA sequencing, which is costly and resource intensive. To address this limitation, we...
Developing an explainable machine learning and fog computing-based visual rating scale for the prediction of dementia progression.
Scientific reports
Jul 16, 2025
Recently, dementia research has primarily concentrated on using Magnetic Resonance Imaging (MRI) to develop learning models in processing and analyzing brain data. However, these models often cannot provide early detection of affected brain regions. ...
Multi-scale machine learning model predicts muscle and functional disease progression.
Scientific reports
Jul 16, 2025
Facioscapulohumeral muscular dystrophy (FSHD) is a genetic neuromuscular disorder characterized by progressive muscle degeneration with substantial variability in severity and progression patterns. FSHD is a highly heterogeneous disease; however, cur...
Objective monitoring of motor symptom severity and their progression in Parkinson's disease using a digital gait device.
Scientific reports
Jul 15, 2025
Digital technologies for monitoring motor symptoms of Parkinson's Disease (PD) underwent a strong evolution during the past years. Although it has been shown for several devices that derived digital gait features can reliably discriminate between hea...
Early neoplastic lesions of the pancreas: initiation, progression, and opportunities for precancer interception.
The Journal of clinical investigation
Jul 15, 2025
Pancreatic ductal adenocarcinoma (PDAC) is known to progress from one of two main precursor lesions: pancreatic intraepithelial neoplasia (PanIN) or intraductal papillary mucinous neoplasm (IPMN). The poor survival rates for patients with PDAC, even ...
Association of dietary quality, biological aging, progression and mortality of cardiovascular-kidney-metabolic syndrome: insights from mediation and machine learning approaches.
Nutrition journal
Jul 7, 2025
BACKGROUND: To investigate the association between the Dietary Inflammatory Index (DII), biological aging, and the staging and mortality of cardiovascular-kidney-metabolic (CKM) syndrome.
Identifying and characterising asthma subgroups at high risk of severe exacerbations using machine learning and longitudinal real-world data.
BMJ health & care informatics
Jul 7, 2025
OBJECTIVES: To identify and characterise distinct subgroups of patients with asthma with severe acute exacerbations (AEs) by using a multistep clustering methodology that combines supervised and unsupervised machine learning.
Multi-omics integration and machine learning uncover molecular basal-like subtype of pancreatic cancer and implicate A2ML1 in promoting tumor epithelial-mesenchymal transition.
Journal of translational medicine
Jul 4, 2025
BACKGROUND: Pancreatic cancer (PC) represents a highly heterogeneous malignancy with poor prognosis, where precise molecular subtyping facilitates comprehensive understanding of disease progression.
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