Early detection of pancreatic ductal adenocarcinoma (PDA) remains a major clinical challenge due to the lack of reliable biomarkers. We developed and validated a machine learning (ML)-based serum protein biomarker panel to enhance PDA diagnosis. Seru...
BACKGROUND: Early diagnosis and intervention in glottic carcinoma (GC) can significantly improve long-term prognosis. However, the accurate diagnosis of early GC is challenging due to its morphological similarity to vocal cord dysplasia, with the dif...
For most cancers, early diagnosis and intervention can significantly improve cure rates and patient survival. Consequently, achieving early and accurate cancer detection has always been a central focus in both medical practice and scientific research...
INTRODUCTION: Breast cancer Mammography (MAM) screening was proven to improve survival worldwide. However, younger patients with higher breast density made MAM less effective in China. It is necessary to establish Chinese-specific effective screening...
BACKGROUND: Early-stage diagnosis of laryngeal cancer significantly improves patient survival and quality of life. However, the scarcity of specialists in low-resource settings hinders the timely review of flexible nasopharyngoscopy (FNS) videos, whi...
OBJECTIVE: Accurate cancer risk prediction is hindered by complex, multi-layered immune interactions, and traditional tissue biopsies are invasive and lack scalability for large-scale or repeated assessments. Peripheral blood offers a minimally invas...
Early diagnosis of skin cancer remains a pressing challenge in dermatological and oncological practice. AI-driven learning models have emerged as powerful tools for automating the classification of skin lesions by using dermoscopic images. This study...
BACKGROUND: Colorectal cancer (CRC) is the third most common cancer worldwide and poses a heavy burden on health care systems. Early screening for CRC through colonoscopy can effectively reduce both the incidence and mortality associated with CRC. Ho...
Data-driven approaches have advanced colorectal lesion diagnosis in digestive endoscopy, yet their application in endocytoscopy (EC)-a high-magnification imaging technique-remains limited, with most studies relying on conventional machine learning me...
In early cancer diagnosis, extracellular vesicles (EVs) are more advantageous than circulating tumor cells due to their smaller size, greater stability, and enhanced tissue penetration. These qualities lead to higher EV concentrations in body fluids,...
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