AIMC Topic: Entropy

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Entropy-driven signal amplification integrated with machine learning in multiplex lateral flow immunoassay for sensitive Point-of-Care colon cancer diagnosis.

Journal of nanobiotechnology
Investigations on epithelial-mesenchymal transition (EMT) events occurring on circulating tumor cells (CTCs) are poised to significantly advance nanoliquid biopsy methodologies. This study presented a colorimetric multiplex lateral flow immunoassay s...

State-space kinetic Ising model reveals task-dependent entropy flow in sparsely active nonequilibrium neuronal dynamics.

Nature communications
Neuronal ensemble activity, including coordinated and oscillatory patterns, exhibits hallmarks of nonequilibrium systems with time-asymmetric trajectories to maintain their organization. However, assessing time asymmetry from neuronal spiking activit...

Predicting and Analyzing Nitrate Adsorption on High-Entropy Alloys Based on Pair Distribution Function Using a Hybrid Machine Learning Framework.

Journal of chemical information and modeling
Incorporating five or more metals into a single structure creates a new family of alloys, high-entropy alloys (HEAs), which hold several exceptional properties, such as outstanding stabilities and continuous electronic structures, making them promisi...

Classifying schizophrenia subtypes via resting-state EEG complexity networks.

Scientific reports
Schizophrenia (SZ) is increasingly recognized as a network disorder marked by abnormal functional connectivity, yet the clinical utility of fMRI remains limited. Electroencephalography (EEG) provides a more practical alternative, though conventional ...

Entropy-Driven Nucleic Acid Amplifier Based on Spatial Confinement as a "Booster" for Detection of Extracellular Vesicle MicroRNAs to Diagnose Gastric Cancer and Monitor Therapeutic Response.

Analytical chemistry
Gastric cancer (GC) continues to pose a significant global health burden with persistent diagnostic challenges, especially in the detection of early-stage GC. Herein, a strand displacement reaction-mediated nucleic acid amplifier based on the spatial...

Machine learning framework for predicting susceptibility to obesity.

Scientific reports
Obesity, currently the fifth leading cause of death worldwide, has seen a significant increase in prevalence over the past four decades. Timely identification of obesity risk facilitates proactive measures against associated factors. In this paper, w...

Information-theoretic multi-scale geometric pre-training for enhanced molecular property prediction.

PloS one
Maximizing information transfer across different structural scales is critical for effective molecular representation learning. Current molecular graph neural networks fail to fully capture the multi-scale nature of molecular geometry, leading to sub...

Histopathological cancer images classification with Deng entropy.

Biomedical physics & engineering express
Histopathological imaging is of paramount importance for the initial detection, diagnosis, and classification of tumors. Recurrent neural networks and convolutional neural networks have led to substantial advancements in digital pathology, thereby en...

Identify Survived Key Features and Relevant Mechanisms for Designing High-Entropy Carbides via AI or Machine Learning.

Journal of chemical information and modeling
Multielement high-entropy carbides (HECs) provide many opportunities for HECs to obtain optimal combinations of various properties, e.g., high strength and high flexibility, leading to high toughness. However, the multielements significantly increase...

MOLECULE: Molecular-dynamics and Optimized deep Learning for Entropy-regularized Classification and Uncertainty-aware Ligand Evaluation.

Journal of chemical theory and computation
Machine learning (ML) and deep learning (DL) methodologies have significantly advanced drug discovery and design in several aspects. Additionally, the integration of structure-based data has proven to successfully support and improve the models' pred...