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Epilepsy, Temporal Lobe

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Global temporal lobe asymmetry as a semi-quantitative imaging biomarker for temporal lobe epilepsy lateralization: A machine learning classification study.

Hellenic journal of nuclear medicine
OBJECTIVE: The purpose of this study was to evaluate the utility of global semi-quantitative analysis via fluorine-18-flurodeoxyglucose positron emission tomography (F-FDG PET) at lateralizing seizure foci and diagnosing patients with unilateral temp...

Machine learning detects EEG microstate alterations in patients living with temporal lobe epilepsy.

Seizure
PURPOSE: Quasi-stable electrical distribution in EEG called microstates could carry useful information on the dynamics of large scale brain networks. Using machine learning techniques we explored if abnormalities in microstates can identify patients ...

A hierarchical multimodal system for motion analysis in patients with epilepsy.

Epilepsy & behavior : E&B
During seizures, a myriad of clinical manifestations may occur. The analysis of these signs, known as seizure semiology, gives clues to the underlying cerebral networks involved. When patients with drug-resistant epilepsy are monitored to assess thei...

Machine learning identifies "rsfMRI epilepsy networks" in temporal lobe epilepsy.

European radiology
OBJECTIVES: Experimental models have provided compelling evidence for the existence of neural networks in temporal lobe epilepsy (TLE). To identify and validate the possible existence of resting-state "epilepsy networks," we used machine learning met...

Detection of mesial temporal lobe epileptiform discharges on intracranial electrodes using deep learning.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
OBJECTIVE: Develop a high-performing algorithm to detect mesial temporal lobe (mTL) epileptiform discharges on intracranial electrode recordings.

Temporal Lobe Epilepsy Surgical Outcomes Can Be Inferred Based on Structural Connectome Hubs: A Machine Learning Study.

Annals of neurology
OBJECTIVE: Medial temporal lobe epilepsy (TLE) is the most common form of medication-resistant focal epilepsy in adults. Despite removal of medial temporal structures, more than one-third of patients continue to have disabling seizures postoperativel...

Voxel-based morphometry analysis and machine learning based classification in pediatric mesial temporal lobe epilepsy with hippocampal sclerosis.

Brain imaging and behavior
Mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE-HS) is a common type of pediatric epilepsy. We sought to evaluate whether the combination of voxel-based morphometry (VBM) and support vector machine (SVM), a machine learning method, was...

A deep learning framework for F-FDG PET imaging diagnosis in pediatric patients with temporal lobe epilepsy.

European journal of nuclear medicine and molecular imaging
PURPOSE: Epilepsy is one of the most disabling neurological disorders, which affects all age groups and often results in severe consequences. Since misdiagnoses are common, many pediatric patients fail to receive the correct treatment. Recently, F-fl...

Neurovascular multiparametric MRI defines epileptogenic and seizure propagation regions in experimental mesiotemporal lobe epilepsy.

Epilepsia
OBJECTIVE: Improving the identification of the epileptogenic zone and associated seizure-spreading regions represents a significant challenge. Innovative brain-imaging modalities tracking neurovascular dynamics during seizures may provide new disease...