AIMC Topic: Fatty Liver

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Deep-learning-based accurate hepatic steatosis quantification for histological assessment of liver biopsies.

Laboratory investigation; a journal of technical methods and pathology
Hepatic steatosis droplet quantification with histology biopsies has high clinical significance for risk stratification and management of patients with fatty liver diseases and in the decision to use donor livers for transplantation. However, patholo...

Predicting and elucidating the etiology of fatty liver disease: A machine learning modeling and validation study in the IMI DIRECT cohorts.

PLoS medicine
BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is highly prevalent and causes serious health complications in individuals with and without type 2 diabetes (T2D). Early diagnosis of NAFLD is important, as this can help prevent irreversible dama...

Ultrasonic liver steatosis quantification by a learning-based acoustic model from a novel shear wave sequence.

Biomedical engineering online
BACKGROUND: An efficient and accurate approach to quantify the steatosis extent of liver is important for clinical practice. For the purpose, we propose a specific designed ultrasound shear wave sequence to estimate ultrasonic and shear wave physical...

Non-invasive diagnosis of non-alcoholic steatohepatitis and fibrosis with the use of omics and supervised learning: A proof of concept study.

Metabolism: clinical and experimental
BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) affects 25-30% of the general population and is characterized by the presence of non-alcoholic fatty liver (NAFL) that can progress to non-alcoholic steatohepatitis (NASH), liver fibrosis and cirr...

Prediction of fatty liver disease using machine learning algorithms.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: Fatty liver disease (FLD) is a common clinical complication; it is associated with high morbidity and mortality. However, an early prediction of FLD patients provides an opportunity to make an appropriate strategy for preven...

Application of Machine Learning Methods to Predict Non-Alcoholic Steatohepatitis (NASH) in Non-Alcoholic Fatty Liver (NAFL) Patients.

AMIA ... Annual Symposium proceedings. AMIA Symposium
Non-alcoholic fatty liver disease (NAFLD) is the leading cause of chronic liver disease worldwide. NAFLD patients have excessive liver fat (steatosis), without other liver diseases and without excessive alcohol consumption. NAFLD consists of a spectr...

Transfer learning with deep convolutional neural network for liver steatosis assessment in ultrasound images.

International journal of computer assisted radiology and surgery
PURPOSE: The nonalcoholic fatty liver disease is the most common liver abnormality. Up to date, liver biopsy is the reference standard for direct liver steatosis quantification in hepatic tissue samples. In this paper we propose a neural network-base...

Computer-assisted liver graft steatosis assessment via learning-based texture analysis.

International journal of computer assisted radiology and surgery
PURPOSE: Fast and accurate graft hepatic steatosis (HS) assessment is of primary importance for lowering liver dysfunction risks after transplantation. Histopathological analysis of biopsied liver is the gold standard for assessing HS, despite being ...

Symtosis: A liver ultrasound tissue characterization and risk stratification in optimized deep learning paradigm.

Computer methods and programs in biomedicine
Background and Objective Fatty Liver Disease (FLD) - a disease caused by deposition of fat in liver cells, is predecessor to terminal diseases such as liver cancer. The machine learning (ML) techniques applied for FLD detection and risk stratificatio...