AIMC Topic: Female

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Screening biomarkers related to cholesterol metabolism in osteoarthritis based on transcriptomics.

Scientific reports Jul 1, 2025
Cholesterol metabolism-related genes (CMRGs) have been associated with osteoarthritis (OA), but their specific regulatory mechanisms remain unclear. This study aimed to investigate the role of CMRGs in OA and provide new insights into its treatment. ...
ROC Curve Protein Interaction Maps Cholesterol Osteoarthritis Clusterin Fatty Acid Synthase, Type I Female Activating Transcription Factor 3 Male Gene Expression Profiling Transcriptome Humans Machine Learning Biomarkers
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Cuff-less blood pressure monitoring via PPG signals using a hybrid CNN-BiLSTM deep learning model with attention mechanism.

Scientific reports Jul 1, 2025
Blood pressure (BP) serves as a fundamental indicator of cardiovascular health, measuring the force exerted by circulating blood against arterial walls during each heartbeat. This paper introduces an advanced deep learning framework for precise, non-...
Male Middle Aged Deep Learning Wearable Electronic Devices Humans Neural Networks, Computer Photoplethysmography Female Blood Pressure Determination Blood Pressure Signal Processing, Computer-Assisted
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Development and validation of a modified SOFA score for mortality prediction in candidemia patients.

Scientific reports Jul 1, 2025
Candidemia is a life-threatening bloodstream infection associated with high mortality rates, particularly in critically ill patients. Accurate risk stratification is crucial for timely intervention and could improve patient outcomes. This study aimed...
Organ Dysfunction Scores Kaplan-Meier Estimate Candidemia Humans Machine Learning Aged Prognosis Male Middle Aged Risk Assessment Critical Illness Intensive Care Units Female
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Predictive model of ulcerative colitis syndrome with ensemble learning and interpretability methods.

Scientific reports Jul 1, 2025
In recent years, the prevalence of chronic diseases such as Ulcerative Colitis (UC) has increased, bringing a heavy burden to healthcare systems. Traditional Chinese Medicine (TCM) stands out for its cost-effective and efficient treatment modalities,...
Humans Machine Learning Prognosis Electronic Health Records Medicine, Chinese Traditional Colitis, Ulcerative Ensemble Learning Female Male Deep Learning
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Anterior cruciate ligament tear detection based on Res2Net modified by improved Lévy flight distribution.

Scientific reports Jul 1, 2025
Anterior Cruciate Ligament (ACL) tears are common in sports and can provide noteworthy health issues. Therefore, accurately diagnosing of tears is important for the early and proper treatment. However, traditional diagnostic methods, such as clinical...
Neural Networks, Computer Algorithms Female Male Deep Learning Magnetic Resonance Imaging Humans Anterior Cruciate Ligament Injuries Anterior Cruciate Ligament
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Ultrasound-based classification of follicular thyroid Cancer using deep convolutional neural networks with transfer learning.

Scientific reports Jul 1, 2025
This study aimed to develop and validate convolutional neural network (CNN) models for distinguishing follicular thyroid carcinoma (FTC) from follicular thyroid adenoma (FTA). Additionally, this current study compared the performance of CNN models wi...
Diagnosis, Differential Adenocarcinoma, Follicular Middle Aged Deep Learning Convolutional Neural Networks Thyroid Gland Thyroid Neoplasms Ultrasonography ROC Curve Female Aged Adult Male Humans Neural Networks, Computer Retrospective Studies
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Prognostic model of lung adenocarcinoma from the perspective of cancer-associated fibroblasts using single-cell and bulk RNA-sequencing.

Scientific reports Jul 1, 2025
Cancer-associated fibroblasts (CAFs) play important roles in the progression of lung adenocarcinoma (LUAD). We examined CAF subgroups via gene ontology, pseudo-time, and cell communication analyses and explored their prognostic value in LUAD using a ...
Machine Learning Prognosis Female Biomarkers, Tumor Humans Cell Proliferation Cell Movement Cancer-Associated Fibroblasts Adenocarcinoma of Lung Single-Cell Analysis Lung Neoplasms Sequence Analysis, RNA Gene Expression Regulation, Neoplastic
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Personalized azithromycin treatment rules for children with watery diarrhea using machine learning.

Nature communications Jul 1, 2025
We use machine learning to identify innovative strategies to target azithromycin to the children with watery diarrhea who are most likely to benefit. Using data from a randomized trial of azithromycin for watery diarrhea (NCT03130114), we develop per...
Treatment Outcome Child, Preschool Precision Medicine Azithromycin Child Humans Female Diarrhea Machine Learning Male Anti-Bacterial Agents Infant
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A machine learning model using clinical notes to identify physician fatigue.

Nature communications Jul 1, 2025
Clinical notes should capture important information from a physician-patient encounter, but they may also contain signals indicative of physician fatigue. Using data from 129,228 emergency department (ED) visits, we train a model to identify notes wr...
Male Emergency Service, Hospital Workload Fatigue Physicians Electronic Health Records Female Humans Machine Learning
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The Future of Questions.

Journal of continuing education in nursing Jul 1, 2025
As we move into the artificial intelligence decade, with more emphasis on creativity and innovation, it will be important to ask questions in a different way. It will be critical for leaders and faculty to think about questions they haven't asked in ...
Adult Humans Male Artificial Intelligence Middle Aged Forecasting Education, Nursing, Continuing Female
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