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Diffusion Histology Imaging Combining Diffusion Basis Spectrum Imaging (DBSI) and Machine Learning Improves Detection and Classification of Glioblastoma Pathology.

Clinical cancer research : an official journal of the American Association for Cancer Research
PURPOSE: Glioblastoma (GBM) is one of the deadliest cancers with no cure. While conventional MRI has been widely adopted to examine GBM clinically, accurate neuroimaging assessment of tumor histopathology for improved diagnosis, surgical planning, an...

Attention-Enriched Deep Learning Model for Breast Tumor Segmentation in Ultrasound Images.

Ultrasound in medicine & biology
Incorporating human domain knowledge for breast tumor diagnosis is challenging because shape, boundary, curvature, intensity or other common medical priors vary significantly across patients and cannot be employed. This work proposes a new approach t...

Radiogenomics for predicting p53 status, PD-L1 expression, and prognosis with machine learning in pancreatic cancer.

British journal of cancer
BACKGROUND: Radiogenomics is an emerging field that integrates "Radiomics" and "Genomics". In the current study, we aimed to predict the genetic information of pancreatic tumours in a simple, inexpensive, and non-invasive manner, using cancer imaging...

Deep Learning-based Automatic Detection Algorithm for Reducing Overlooked Lung Cancers on Chest Radiographs.

Radiology
Background It is uncertain whether a deep learning-based automatic detection algorithm (DLAD) for identifying malignant nodules on chest radiographs will help diagnose lung cancers. Purpose To evaluate the efficacy of using a DLAD in observer perform...

Capsule networks as recurrent models of grouping and segmentation.

PLoS computational biology
Classically, visual processing is described as a cascade of local feedforward computations. Feedforward Convolutional Neural Networks (ffCNNs) have shown how powerful such models can be. However, using visual crowding as a well-controlled challenge, ...

Cortical surface registration using unsupervised learning.

NeuroImage
Non-rigid cortical registration is an important and challenging task due to the geometric complexity of the human cortex and the high degree of inter-subject variability. A conventional solution is to use a spherical representation of surface propert...

A machine learning approach for mortality prediction only using non-invasive parameters.

Medical & biological engineering & computing
At present, the traditional scoring methods generally utilize laboratory measurements to predict mortality. It results in difficulties of early mortality prediction in the rural areas lack of professional laboratorians and medical laboratory equipmen...

Machine-learning approach to predict on-road driving ability in healthy older people.

Psychiatry and clinical neurosciences
AIM: In Japan, fatal traffic accidents due to older drivers are on the rise. Considering that approximately half the older drivers who have caused fatal accidents are cognitively normal healthy people, it has been required to detect older drivers who...

Reproductive outcomes predicted by phase imaging with computational specificity of spermatozoon ultrastructure.

Proceedings of the National Academy of Sciences of the United States of America
The ability to evaluate sperm at the microscopic level, at high-throughput, would be useful for assisted reproductive technologies (ARTs), as it can allow specific selection of sperm cells for in vitro fertilization (IVF). The tradeoff between intrin...

Early detection of type 2 diabetes mellitus using machine learning-based prediction models.

Scientific reports
Most screening tests for T2DM in use today were developed using multivariate regression methods that are often further simplified to allow transformation into a scoring formula. The increasing volume of electronically collected data opened the opport...