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Modelling disease risk for amyloid A (AA) amyloidosis in non-human primates using machine learning.

Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis
Amyloid A (AA) amyloidosis is found in humans and non-human primates, but quantifying disease risk prior to clinical symptoms is challenging. We applied machine learning to identify the best predictors of amyloidosis in rhesus macaques from availabl...

Deep Learning-based Image Conversion of CT Reconstruction Kernels Improves Radiomics Reproducibility for Pulmonary Nodules or Masses.

Radiology
Background Intratumor heterogeneity in lung cancer may influence outcomes. CT radiomics seeks to assess tumor features to provide detailed imaging features. However, CT radiomic features vary according to the reconstruction kernel used for image gene...

Predicting Breast Cancer by Applying Deep Learning to Linked Health Records and Mammograms.

Radiology
Background Computational models on the basis of deep neural networks are increasingly used to analyze health care data. However, the efficacy of traditional computational models in radiology is a matter of debate. Purpose To evaluate the accuracy and...

CT Super-Resolution GAN Constrained by the Identical, Residual, and Cycle Learning Ensemble (GAN-CIRCLE).

IEEE transactions on medical imaging
In this paper, we present a semi-supervised deep learning approach to accurately recover high-resolution (HR) CT images from low-resolution (LR) counterparts. Specifically, with the generative adversarial network (GAN) as the building block, we enfor...

Microvascularity detection and quantification in glioma: a novel deep-learning-based framework.

Laboratory investigation; a journal of technical methods and pathology
Microvascularity is highly correlated with the grading and subtyping of gliomas, making this one of its most important histological features. Accurate quantitative analysis of microvessels is helpful for the development of a targeted therapy for anti...

SIMON, an Automated Machine Learning System, Reveals Immune Signatures of Influenza Vaccine Responses.

Journal of immunology (Baltimore, Md. : 1950)
Machine learning holds considerable promise for understanding complex biological processes such as vaccine responses. Capturing interindividual variability is essential to increase the statistical power necessary for building more accurate predictive...

Automatic CIN Grades Prediction of Sequential Cervigram Image Using LSTM With Multistate CNN Features.

IEEE journal of biomedical and health informatics
Cervical cancer ranks as the second most common cancer in women worldwide. In clinical practice, colposcopy is an indispensable part of screening for cervical intraepithelial neoplasia (CIN) grades and cervical cancer but exhibits high misdiagnosis r...

Development of Machine Learning Algorithms for Prediction of Sustained Postoperative Opioid Prescriptions After Total Hip Arthroplasty.

The Journal of arthroplasty
BACKGROUND: Postoperative recovery after total hip arthroplasty (THA) can lead to the development of prolonged opioid use but there are few tools for predicting this adverse outcome. The purpose of this study is to develop machine learning algorithms...

The Ventral Visual Pathway Represents Animal Appearance over Animacy, Unlike Human Behavior and Deep Neural Networks.

The Journal of neuroscience : the official journal of the Society for Neuroscience
Recent studies showed agreement between how the human brain and neural networks represent objects, suggesting that we might start to understand the underlying computations. However, we know that the human brain is prone to biases at many perceptual a...