Osteoporosis is a chronic disease characterized by a progressive decline in bone density and quality, leading to increased bone fragility and a higher susceptibility to fractures, even in response to minimal trauma. Osteoporotic fractures represent a...
Inflammatory responses play a crucial role in the progression of pediatric neurogenic bladder (NB)-associated fibrosis; however, their specific contributions remain poorly understood. This study aimed to identify inflammation-related biomarkers for d...
Ecotoxicology and environmental safety
Sep 1, 2025
Our aim is to evaluate the association of prenatal exposure to per- and polyfluoroalkyl substances (PFAS) with offspring blood pressure (BP); examine the moderating effect of children's age; and the mediating effects of inflammatory cytokines. Data o...
European journal of clinical pharmacology
Sep 1, 2025
PURPOSE: This study develops and compares population pharmacokinetics (PopPK) models and machine learning methods, including neural networks, to predict steady-state trough concentrations in pediatric patients and provide improved dosing recommendati...
AIM: Chronic obstructive pulmonary disease (COPD) and heart failure (HF) are closely intertwined comorbidities that present significant clinical challenges due to the poorly understood pathophysiological mechanisms driving their coexistence. In this ...
Embryo selection is an indispensable step to ensure the success of In-Vitro Fertilization; however, this decision is a time-consuming, laborious, and highly subjective task for embryologists. In the best scenarios, when implanting an embryo of the be...
Accurately predicting cognitive scores based on structural MRI holds significant clinical value for understanding the pathological stages of dementia and forecasting Alzheimer's disease (AD). Some existing deep learning methods often depend on anatom...
Feature selection using evolutionary algorithms-a well-liked technique for choosing pertinent characteristics in huge datasets is explored. In machine learning, feature selection (FS) is a key phase that helps to boost model efficiency, decrease over...
BACKGROUND: Sleep apnea (SA), a prevalent sleep-related breathing disorder, disrupts normal respiratory patterns during sleep. This disruption can have a cascading effect on the body, potentially leading to complications in various organs, including ...
Respiratory and cardiovascular diseases represent a significant global health burden, underscoring the need for innovative, accessible, and cost-effective screening solutions. This study introduces a clinically grounded framework for the early detect...
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