BACKGROUND: Atypical Parkinsonian Syndromes (APS) form the third largest group of neurodegenerative disorders including Progressive Supranuclear Palsy (PSP), Multiple System Atrophy (MSA), and Corticobasal Syndrome (CBS). These conditions are charact...
BACKGROUND: The exact mechanism of graft dysfunction has not been fully clarified. We aimed to explore the causal effects of serum metabolites on graft dysfunction and the mediating role of inflammatory proteins.
This study investigates temperature impacts on preterm birth (PTB) using residential address GPS coordinates for 311,972 pregnant women in Wuhan, China, coupled with daily environmental data. We developed a machine learning model to analyze the impac...
The neural mechanisms underlying resting-state cerebral functional activity in bipolar disorder (BD) and the effects of pharmacotherapy on it remain unclear. This study investigated changes in local brain activity in BD patients (BDPs) following trea...
BACKGROUND: Early detection of cancer therapy-related cardiac dysfunction (CTRCD) after anthracycline exposure is critically important in minimizing morbidity and mortality. Artificial intelligence models applied to electrocardiograms (ECG-AI) may al...
AIMS: To investigate the value of multi-parametric magnetic resonance imaging (MRI)-based deep learning (DL) in predicting the Lymphovascular Invasion (LVI) status of invasive breast ductal cancer (IBDC).
Clinical nutrition (Edinburgh, Scotland)
Jun 25, 2025
BACKGROUND & AIMS: Studies in-vitro and in animals propose that vitamins and minerals can alter the human gut microbiome. Human trials replicating these findings are scarce or used micronutrient supplementation in supraphysiological doses. We explore...
Journal of plastic, reconstructive & aesthetic surgery : JPRAS
Jun 25, 2025
BACKGROUND: Nipple-sparing mastectomy (NSM) with immediate implant-based breast reconstruction provides aesthetic and psychosocial benefits, but nipple-areolar complex (NAC) necrosis remains a significant risk. This study externally validated a previ...
INTRODUCTION: Systemic sclerosis (SSc) is a complex inflammatory vasculopathy with diverse symptoms and variable disease progression. Despite its known impact on body composition (BC), clinical decision-making has yet to incorporate these biomarkers....
BACKGROUND: With a focus on postoperative dysfunctions that may occur after maxillofacial tumor resection and the difficulties faced during home rehabilitation, we developed a mobile health app based on nurse-patient cooperation. The app extends reha...
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