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Computed tomography-based nnU-Net for region-specific brain structural changes across the alzheimer's continuum and frontotemporal dementia subtypes.

Scientific reports
Quantifying structural brain changes is critical for diagnosing and monitoring neurodegenerative diseases. Although magnetic resonance imaging (MRI) is the silver standard, limited accessibility and cost hamper routine use. We developed a deep learni...

Enhanced hybrid deep neural network for EEG-based schizophrenia diagnosis using functional and temporal features.

Scientific reports
Schizophrenia is a complex psychiatric disorder that disrupts cognition, emotions, and social behavior. Timely and accurate diagnosis is essential for effective treatment. Traditional diagnostic methods relying on clinical assessments have limitation...

Development and validation of an interpretable predictive machine learning model for successful weaning of continuous renal replacement therapy.

Scientific reports
Continuous renal replacement therapy (CRRT) is a vital intervention for critically ill patients with severe acute kidney injury, yet no standardized criteria exist to determine the optimal time for its discontinuation. We developed and validated mach...

Machine learning classification of inflammatory bowel disease activity using white blood cell subsets.

BMJ open gastroenterology
OBJECTIVE: The lack of a rapid, validated, consistent test for tracking disease activity in patients with inflammatory bowel disease (IBD) is currently a major challenge. Currently used biomarkers have notable disadvantages, such as the slow processi...

Determining the Feasibility and Usability of a Co-Designed Culturally Appropriate Conversational Agent (DESI-Heart) to Support Self-Care in People With Cardiovascular Diseases: Protocol for a Single-Arm Pilot Trial.

JMIR research protocols
BACKGROUND: Cardiovascular diseases (CVDs) are a leading cause of death and disability worldwide. For people living with CVD, clinical guidelines recommend ongoing self-care such as symptom monitoring, medication adherence, and lifestyle modification...

Evaluation of an AI-Based Chatbot Providing Real-Time Feedback in Communication Training for Mental Health Care Professionals: Proof-of-Concept Observational Study.

Journal of medical Internet research
BACKGROUND: Effective communication is essential in medical practice, especially in dealing with the increasing number of patients presenting with mental health conditions. Feedback plays a crucial role in improving communication skills but is often ...

Comparison of ChatGPT and DeepSeek on a Standardized Audiologist Qualification Examination in Chinese: Observational Study.

JMIR formative research
BACKGROUND: Generative artificial intelligence (GenAI), exemplified by ChatGPT and DeepSeek, is rapidly advancing and reshaping human-computer interaction with its growing reasoning capabilities and broad applications across fields such as medicine a...

Center-surround inhibition in expectation and its underlying computational and artificial neural network models.

eLife
Expectation is beneficial for adaptive behavior through quickly deducing plausible interpretations of information. The profile and underlying neural computations of this process, however, remain unclear. When participants expected a grating with a sp...