AIMC Topic: Gastrointestinal Microbiome
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Interpretive prediction of hyperuricemia and gout patients via machine learning analysis of human gut microbiome.
BMC microbiology
Jul 10, 2025
Hyperuricemia (HUA) and gout result from imbalances in uric acid metabolism and are closely associated with the gut microbiota. Advanced analytical methods facilitate the exploration of microbiota complexity. In this study, 16S rRNA sequencing data f...
Gut microbiota composition is related to anxiety and aggression scores in companion dogs.
Scientific reports
Jul 8, 2025
There is mounting evidence for a link between behaviour and the gut microbiome in animal and human health. However, the role of the gut microbiome in the development and severity of behavioural issues in companion dogs is not yet fully understood. He...
Multi-kingdom microbiota analysis reveals bacteria-viral interplay in IBS with depression and anxiety.
NPJ biofilms and microbiomes
Jul 5, 2025
Irritable Bowel Syndrome (IBS) is a common gastrointestinal disorder frequently accompanied by psychological symptoms. Bacterial microbiota plays a critical role in mediating local and systemic immunity, and alterations in these microbial communities...
Gut microbiome alterations and hepatic encephalopathy post-TIPS in liver cirrhosis patients.
Journal of translational medicine
Jul 4, 2025
BACKGROUND: The transjugular intrahepatic portosystemic shunt (TIPS), a crucial tool for treating complications related to portal hypertension in patients with liver cirrhosis, is often associated with an increased risk of postoperative complications...
Associations between weight gain, integrase inhibitors antiretroviral agents, and gut microbiome in people living with HIV: a cross-sectional study.
Scientific reports
Jul 2, 2025
Dolutegravir and bictegravir are second-generation HIV integrase strand transfer inhibitors (INSTIs) that were previously associated with abnormal weight gain. This monocentric cross-sectional study investigates associations between weight gain durin...
Targeted metabolomics reveals bioactive inflammatory mediators from gut into blood circulation in children with NAFLD.
NPJ biofilms and microbiomes
Jul 1, 2025
Altered gut metabolites are important for the inflammatory progression in children with NAFLD. Fecal and plasma samples were collected from 145 subjects including 53 non-alcoholic fatty liver (NAFL), 39 nonalcoholic steatohepatitis (NASH) and 53 obes...
Micronutrient supplementation influences the composition and diet-originating function of the gut microbiome in healthy adults.
Clinical nutrition (Edinburgh, Scotland)
Jun 25, 2025
BACKGROUND & AIMS: Studies in-vitro and in animals propose that vitamins and minerals can alter the human gut microbiome. Human trials replicating these findings are scarce or used micronutrient supplementation in supraphysiological doses. We explore...
Enzymatic carbon-fluorine bond cleavage by human gut microbes.
Proceedings of the National Academy of Sciences of the United States of America
Jun 13, 2025
Fluorinated compounds are used for agrochemical, pharmaceutical, and numerous industrial applications, resulting in global contamination. In many molecules, fluorine is incorporated to enhance the half-life and improve bioavailability. Fluorinated co...
Mucosal immune responses and intestinal microbiome associations in wild spotted hyenas (Crocuta crocuta).
Communications biology
Jun 13, 2025
Little is known about host-gut microbiome interactions within natural populations at the intestinal mucosa, the primary interface. We investigate associations between the intestinal microbiome and mucosal immune measures while controlling for host, s...
Gut microbiota alterations are linked to COVID-19 severity in North African and European populations.
NPJ biofilms and microbiomes
Jun 13, 2025
Although COVID-19 primarily affects the respiratory system, many patients experience gastrointestinal symptoms, suggesting a role for the gut microbiota in disease pathogenesis. To explore this, we performed shotgun metagenomic sequencing on stool sa...
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