Current opinion in organ transplantation
Jun 1, 2025
PURPOSE OF REVIEW: The objective of this review is to provide an update on the application of artificial intelligence (AI) for the histological interpretation of kidney transplant biopsies.
Liver transplant recipients (LTRs) are at risk of graft injury, leading to cirrhosis and reduced survival. Liver biopsy, the diagnostic gold standard, is invasive and risky. We developed a hybrid multi-class neural network (NN) model, 'GraftIQ,' inte...
Studies in health technology and informatics
May 15, 2025
A significant risk following a kidney transplantation is graft loss. The Screen Reject Project has developed a Clinical Data Warehouse (CDWH) as a foundation for a clinical decision support system designed to improve the diagnosis of graft rejections...
BACKGROUND AND AIM: Liver transplant (LT) recipients may succumb to graft-related pathologies, contributing to graft fibrosis (GF). Current methods to diagnose GF are limited, ranging from procedural-related complications to low accuracy. With recent...
BACKGROUND: Chronic rejection forms the leading cause of late graft loss in pediatric kidney transplant recipients. Despite improvement in short-term graft outcomes, chronic rejection impedes comparable progress in long-term graft outcomes.
Acute allograft rejection in patients undergoing renal transplantation is diagnosed through histopathological analysis of renal graft biopsies, which can be used to quantify elementary lesions. However, quantification of elementary lesions requires c...
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
Nov 30, 2023
BACKGROUND: Interstitial inflammation and peritubular capillaritis are observed in many diseases on native and transplant kidney biopsies. A precise and automated evaluation of these histological criteria could help stratify patients' kidney prognose...
Studies in health technology and informatics
Aug 21, 2019
Kidney transplantation is recommended for patients with End-Stage Renal Disease (ESRD). However, complications, such as graft rejection are hard to predict due to donor and recipient variability. This study discusses the role of machine learning (ML)...
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